Cognitive Disorders and Metabolism in 18-FDG- PET in Hereditary Spastic Paraplegia Type 4 (SPG4)
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Observational
SUMMARY
Hereditary spastic paraplegia type 4 is the most frequent mutation of hereditary spastic paraplegias. It is commonly described as pure, with progressive weakness of the lower limbs, pyramidal syndrome and vesico-sphincter disorders. However, cognitive disorders have been reported for over 20 years, but remain poorly characterized.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Patient over 18 years of age, living in the Grand Est region (France)
• Patient with a pathogenic or probably pathogenic variant (class 4 or 5) in the SPAST gene.
Locations
Other Locations
France
Centre hospitalier régional universitaire
RECRUITING
Nancy
Contact Information
Primary
Mathilde Renaud
m.renaud2@chru-nancy.fr
+333 83 85 17 80
Time Frame
Start Date: 2022-01-01
Estimated Completion Date: 2025-01-02
Participants
Target number of participants: 30
Related Therapeutic Areas
Sponsors
Leads: Central Hospital, Nancy, France