Characteristics And Clinical Course Of Disease In Participants With Cardiomyopathy Associated With Friedreich Ataxia (CLARITY-FA)
Status: Recruiting
Location: See all (4) locations...
Study Type: Observational
SUMMARY
Characteristics and clinical course of disease In participants with cardiomyopathy associated with Friedreich Ataxia (CLARITY-FA)
Eligibility
Participation Requirements
Sex: All
Minimum Age: 6
View:
• Male or female, ages ≥6 years at the time of signing the informed consent (and assent, if applicable).
• Diagnosis of FA, based on clinical phenotype and genotype (GAA expansion on both alleles), with onset of FA occurring at ≤25 years of age
• Confirmed left ventricular hypertrophy (LVH)
• Left ventricular ejection fraction ≥40%
Locations
United States
California
University of California San Diego
RECRUITING
La Jolla
Florida
University of South Florida
RECRUITING
Tampa
Missouri
Washington University School of Medicine in St. Louis
RECRUITING
St Louis
Other Locations
Canada
Centre Hospitalier de Universite de Montreal (CHUM)
RECRUITING
Montreal
Contact Information
Primary
Lexeo Clinical Trials
clinicaltrials@lexeotx.com
212-547-9879
Time Frame
Start Date: 2025-09-30
Estimated Completion Date: 2027-09
Participants
Target number of participants: 65
Treatments
Cohort 1: Participants ≥16 years of age with FA-CM
Participants ≥16 years of age with FA-CM
Cohort 2: Participants 6 to <16 years of age with FA-CM
Participants 6 to \<16 years of age with FA-CM
Related Therapeutic Areas
Sponsors
Leads: Lexeo Therapeutics