Individualized Neuro-Modulation Paired With Cerebellar Therapy
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this project is to evaluate feasibility and preliminary efficacy of pairing personalized transcranial direct current stimulation (tDCS) with individualized rehabilitation therapy in people with cerebellar damage.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Age 18-75 years
• Males and Females
• Disorders that predominantly affect the cerebellum: damage from stroke, tumor or degeneration (genetic or non-genetic causes, congenital hypoplasia).
Locations
United States
Maryland
Motion Analysis Lab in the Kennedy Krieger Institute
RECRUITING
Baltimore
Contact Information
Primary
Derek J Eversley, BS
eversley@kennedykrieger.org
443-923-2716
Backup
Anthony J Gonzalez, BS
gonzalezan@kennedykrieger.org
443-923-2716
Time Frame
Start Date: 2026-06-30
Estimated Completion Date: 2032-12-02
Participants
Target number of participants: 30
Treatments
Experimental: Active stimulation combined with therapy.
Once a stimulation site is determined, subjects will receive 20 minutes of active tDCS stimulation daily. Subjects will also receive one hour of therapy, twice daily. Therapy will be individualized to each subject and, will encompass three domains; 1) walking and balance control, 2) hand dexterity and arm control, 3)speech articulation, prosody, and intelligibility. Subjects will complete up to 30 therapy sessions.
Sham_comparator: Sham stimulation combined with therapy.
Once a stimulation site is determined, subjects will receive 20 minutes of sham tDCS stimulation daily. Subjects will also receive one hour of therapy, twice daily. Therapy will be individualized to each subject and, will encompass three domains; 1) walking and balance control, 2) hand dexterity and arm control, 3)speech articulation, prosody, and intelligibility. Subjects will complete up to 30 therapy sessions.
Related Therapeutic Areas
Sponsors
Collaborators: Once Upon a Time Foundation
Leads: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.