Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

The VASCULAID-RETRO study, within the broader VASCULAID project, aims to create artificial intelligence (AI) algorithms that can predict cardiovascular events and the progression of abdominal aortic aneurysm (AAA) and peripheral arterial disease (PAD). The study plans to gather and analyze data from at least 5000 AAA and 6000 PAD patients, combining existing cohorts and retrospectively collected data. During this project, AI tools will be developed to perform automatic anatomical segmentation and analyses on multimodal imaging. AI prediction algorithms will be developed based on multisource data (imaging, medical history, -omics).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 90
Healthy Volunteers: f
View:

• Males and females, 40-90 years old, with an AAA \>3cm. This includes patients with infrarenal, juxtarenal, suprarenal, iliac (defined as 1.5x its normal diameter) aneurysms, as well as mycotic aneurysms. Patients that have had interventions or ruptures will also be included

• Males and females, 40-90 years old, all PAD patients (Fontaine stages 1,2,3, and 4).

Locations
Other Locations
Finland
Hospital District of Helsinki and Uusimaa (HUS)
RECRUITING
Helsinki
Germany
Asklepios kliniken hamburg
RECRUITING
Hamburg
Netherlands
Amsterdam UMC
RECRUITING
Amsterdam
Portugal
University Hospital Center of São João
RECRUITING
Porto
Serbia
University Clinical Centre of Serbia
RECRUITING
Belgrade
United Kingdom
Oxford University Hospitals
RECRUITING
Oxford
Contact Information
Primary
Kak Khee Yeung, MD, PhD
k.yeung@amsterdamumc.nl
+31 6 14278725
Backup
Lotte Rijken, Msc.
l.rijken@amsterdamumc.nl
Time Frame
Start Date: 2023-10-31
Estimated Completion Date: 2029-05-01
Participants
Target number of participants: 11000
Treatments
Abdominal Aortic Aneurysm patients
Peripheral Arterial Disease patients
Sponsors
Collaborators: Asklepios Kliniken Hamburg GmbH, Faculty of Medicine, University of Belgrade, University of Bergen, Brightfish Be, VINČA INSTITUTE OF NUCLEAR SCIENCES Belgrado, Technical University of Twente, Universidade do Porto, Hospital District of Helsinki and Uusimaa, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Centre Hospitalier Universitaire de Nice, Stichting Allai, University of Oxford
Leads: Amsterdam UMC, location VUmc

This content was sourced from clinicaltrials.gov