Investigating Inhibitory Control Networks in Parkinson's Disease

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Eligible for surgery based on multi-disciplinary consensus review

• Have a diagnosis of Parkinson's disease or Essential Tremor

• Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)

• Willingness to participate in the paradigms described in the protocol

Locations
United States
Alabama
University of Alabama at Birmingham
RECRUITING
Birmingham
Contact Information
Primary
Nicole Bentley, MD
jbentley@uabmc.edu
205-975-0011
Time Frame
Start Date: 2021-04-01
Estimated Completion Date: 2028-03-31
Participants
Target number of participants: 140
Treatments
Experimental: Treatment
Parkinson's Disease Patients receiving DBS electrodes
No_intervention: Control
Control subjects will be non-Parkinson's Disease patients with essential tremor
Sponsors
Leads: University of Alabama at Birmingham
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)

This content was sourced from clinicaltrials.gov

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