Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to investigate the brain activity associated with motor and non-motor symptoms of movement disorders, including Parkinson's disease (PD) and essential tremor. These movement disorders commonly have significant non-motor features, such as depression, cognitive and memory impairment, decreased attention, speech and language disturbances, and slower processing speeds. The investigators are interested in the brain activity associated with these motor and non-motor symptoms, and propose to investigate changes in brain activity while the investigators perform recordings of the surface and deep structures of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Eligible for DBS surgery based on multi-disciplinary consensus review

• Have a diagnosis of Parkinson's disease or Essential Tremor

• A minimum of 18 years of age

• Willingness to participate in the paradigms described in the protocol

Locations
United States
Alabama
University of Alabama at Birmingham
RECRUITING
Birmingham
Contact Information
Primary
Nicole Bentley, MD
jbentley@uabmc.edu
205-975-0011
Time Frame
Start Date: 2019-09-01
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 90
Treatments
Experimental: Treatment
Parkinson's Disease Patients receiving DBS electrodes
No_intervention: Control
Control subjects will be non-Parkinson's Disease patients with essential tremor
Sponsors
Leads: University of Alabama at Birmingham

This content was sourced from clinicaltrials.gov

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