Chronic Stimulation of the Motor Ventral Thalamus (VOP/VIM) for Motor Control in Humans

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to recruit patients already implanted with Deep Brain Stimulation (DBS) for movement disorders to complete tasks assessing parameters of motor output, speech, and swallowing functions, both with and without stimulation. DBS parameters would be adjusted prior to motor testing. Patients would then participate in multiple sessions performing contralateral upper extremity movement tasks measuring movement speed, grip strength, and strength modulation, facial movement, swallowing, and speech tasks.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:

⁃ ALL PATIENTS:

• Age lower than 80 to better tolerate intraoperative testing.

• All Movement disorder patients, older than 18 and younger than 80, who will be implanted with DBS for treatment of motor symptoms.

⁃ HEALTHY CONTROLS:

• Subject has provided written informed consent and Health Insurance Portability and Accountability Act (HIPAA) authorization, where applicable, prior to any study-related procedures.

• Subject is ≥18 years of age and \< 80 years of age.

• Subject is willing and able to comply with scheduled visits and study procedures.

Locations
United States
Pennsylvania
University of Pittsburgh
RECRUITING
Pittsburgh
Contact Information
Primary
Cierra Clark, MS
cic27@pitt.edu
240-441-4216
Backup
Elvira Pirondini, PhD
elvirap@pitt.edu
412-636-0595
Time Frame
Start Date: 2022-05-10
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 60
Treatments
Experimental: Deep Brain Stimulation of the Motor Thalamus
Individuals with deep brain stimulation device implanted in the motor thalamus for movement disorders treatment who also sustain speech, swallowing, and motor deficits.
No_intervention: Healthy Control Participants
The investigators aim to include healthy control subjects who will complete the language and upper-limb tasks. The healthy subjects will not undergo any surgical procedures.
Sponsors
Leads: University of Pittsburgh

This content was sourced from clinicaltrials.gov