Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity- AIM 1
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 70
Healthy Volunteers: t
View:
• Undergoing gastric bypass surgery
• Confirmed AUROC F=0 or F\>2 liver fibrosis
• Age 30-70 years
• BMI greater than 40 kg/m2
• Negative pregnancy test (female only)
• Lab Values: Normal TSH
Locations
United States
Arizona
Mayo Clinic in Arizona
RECRUITING
Scottsdale
Contact Information
Primary
Keegan M Stewart
stewart.keegan@mayo.edu
480-301-4164
Time Frame
Start Date: 2022-02-20
Estimated Completion Date: 2025-12
Participants
Target number of participants: 60
Treatments
Weight loss surgery
Gastric bypass surgery will be followed by weight loss as standard of care. Liver fibrosis by elastography will be determined before surgery.
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic