The Clinical Efficacy of Laparoscopic Partial Splenectomy for Hypersplenism in Liver Cirrhosis Patients
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
In this study,the researchers compared the changes in immune function-related indicators in patients with liver cirrhosis following laparoscopic partial splenectomy,to determine whether this surgical intervention can enhance postoperative immune function and thereby improve patient outcomes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
• Splenomegaly with secondary hypersplenism
• gastroesophageal variceal bleeding
• Informed consent to participate in the study
Locations
Other Locations
China
Clinical Medical College of Yangzhou University
RECRUITING
Yangzhou
Contact Information
Primary
Guo-Qing Jiang
jgqing2003@hotmail.com
+8651487373382
Backup
Dou-Sheng Bai
jgqing2003@hotmail.com
+8651487373382
Time Frame
Start Date: 2025-09-24
Estimated Completion Date: 2028-09-24
Participants
Target number of participants: 30
Treatments
No_intervention: laparoscopic splenectomy
Patients in this arm undergo the standard laparoscopic splenectomy procedure, which serves as the active comparator. The entire spleen is removed after careful dissection and ligation of the splenic hilum.
Experimental: laparoscopic partial splenectomy
The laparoscopic partial splenectomy technique involved preserving the short gastric vessels and the splenic suspensory ligament, with resection conducted along the demarcation line.
Related Therapeutic Areas
Sponsors
Leads: Northern Jiangsu People's Hospital