Distinguished in Cholangiocarcinoma (Bile Duct Cancer)

Dr. Efrat Dotan

Hematology | Oncology
Penn Medicine
LG Health Physicians Hematology And Medical Oncology
2102 Harrisburg Pike, 
Lancaster, PA 
On Staff At
Clinical Trials:Currently Recruiting for 1 Trial
Accepting New Patients

Distinguished in Cholangiocarcinoma (Bile Duct Cancer)
Penn Medicine
LG Health Physicians Hematology And Medical Oncology
2102 Harrisburg Pike, 
Lancaster, PA 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

Efrat Dotan is a Hematologist and an Oncologist in Lancaster, Pennsylvania. Dr. Dotan is rated as a Distinguished provider by MediFind in the treatment of Cholangiocarcinoma (Bile Duct Cancer). Her top areas of expertise are Pancreatic Cancer, Colorectal Cancer, Familial Colorectal Cancer, and Cholangiocarcinoma (Bile Duct Cancer). Dr. Dotan is currently accepting new patients.

Her clinical research consists of co-authoring 95 peer reviewed articles and participating in 14 clinical trials. MediFind looks at clinical research from the past 15 years. In particular, she has co-authored 3 articles and participated in 2 clinical trials in the study of Cholangiocarcinoma (Bile Duct Cancer).

Graduate Institution
Technion - Israel Institute Of Technology
Residency
Lenox Hill Hospital
Specialties
Hematology
Oncology
Licenses
Internal Medicine in PA
Board Certifications
Medical Oncology, 2010
Fellowships
Fox Chase Cancer Center
Hospital Affiliations
Lancaster General Hospital
Temple University Hospital
Languages Spoken
English
Gender
Female

Insurance

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Accepted insurance plans:

Aetna
  • EPO
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  • POS
  • PPO
Anthem
  • EPO
  • HMO
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Avalon Health Care
  • MEDICARE PDP
Blue Cross Blue Shield
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Capital Blue Cross
  • INSURANCE PLAN
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  • OTHER MEDICARE PART D
  • PPO
Cigna
  • EPO
  • HMO
  • PPO
Gateway Health Plan
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
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Geisinger
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Health Partners Plans
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UnitedHealthcare
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UPMC
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  • PPO
Wellcare
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  • OTHER MEDICARE PART D
View 14 Less Insurance Carriers -

Locations

LG Health Physicians Hematology and Medical Oncology
2102 Harrisburg Pike, Lancaster, PA 17601
Call: 717-544-9400

Additional Areas of Focus

Dr. Dotan has provided the following conditions as areas of focus. Please note that we may not have enough data to validate their experience in some of these conditions.

Esophageal Cancer
Gallbladder Cancer
Pancreatic Cancer
Colorectal Cancer
Anal Cancer
Liver Cancer

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


14 Clinical Trials

Window of Opportunity for Neoadjuvant Stroma Modification in Pancreatic Cancer
Window of Opportunity for Neoadjuvant Stroma Modification in Pancreatic Cancer
Enrollment Status: Recruiting
Publish Date: April 16, 2025
Intervention Type: Other, Combination product
Study Phase: Early Phase 1
A Phase 2 Study of Pevonedistat in Combination With Carboplatin and Paclitaxel in Advanced Intrahepatic Cholangiocarcinoma
A Phase 2 Study of Pevonedistat in Combination With Carboplatin and Paclitaxel in Advanced Intrahepatic Cholangiocarcinoma
Enrollment Status: Active_not_recruiting
Publish Date: November 17, 2025
Intervention Type: Drug
Study Drugs: Carboplatin, Paclitaxel, Pevonedistat
Study Phase: Phase 2
Redefining The Use Of A FOLFIRINOX-Like Regimen In the Front Line In Older Patients With Metastatic Pancreatic Cancer
Redefining The Use Of A FOLFIRINOX-Like Regimen In the Front Line In Older Patients With Metastatic Pancreatic Cancer
Enrollment Status: Active_not_recruiting
Publish Date: November 13, 2025
Intervention Type: Drug
Study Phase: Phase 2
Clinical and Biological Predictors of Chemotherapy Toxicity in Older Adults
Clinical and Biological Predictors of Chemotherapy Toxicity in Older Adults
Enrollment Status: Active_not_recruiting
Publish Date: November 07, 2025
A Phase 2/3, Randomized, Open-Label Study of Maintenance GRT-C901/GRT-R902, A Neoantigen Vaccine, in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer
A Phase 2/3, Randomized, Open-Label Study of Maintenance GRT-C901/GRT-R902, A Neoantigen Vaccine, in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer
Enrollment Status: Active_not_recruiting
Publish Date: May 16, 2025
Intervention Type: Drug
Study Phase: Phase 2/Phase 3
A Phase 1 Study of ZW49 in Patients With Locally Advanced (Unresectable) or Metastatic HER2-Expressing Cancers
A Phase 1 Study of ZW49 in Patients With Locally Advanced (Unresectable) or Metastatic HER2-Expressing Cancers
Enrollment Status: Completed
Publish Date: January 29, 2025
Intervention Type: Drug
Study Drug: ZW49
Study Phase: Phase 1
Regorafenib in Adults 70 Years or Older With Metastatic Colorectal Cancer: A Phase II Study
Regorafenib in Adults 70 Years or Older With Metastatic Colorectal Cancer: A Phase II Study
Enrollment Status: Completed
Publish Date: September 04, 2024
Intervention Type: Drug
Study Drug: Regorafenib
Study Phase: Phase 2
A Phase I/II Study of Once or Twice Weekly IMMU-130 (hMN-14-SN38, Antibody-Drug Conjugate) in Patients With Colorectal Cancer
A Phase I/II Study of Once or Twice Weekly IMMU-130 (hMN-14-SN38, Antibody-Drug Conjugate) in Patients With Colorectal Cancer
Enrollment Status: Terminated
Publish Date: January 24, 2024
Intervention Type: Drug
Study Phase: Phase 1/Phase 2
A Phase I and Randomized Phase II Study of Nab-Paclitaxel/Gemcitabine With or Without AZD1775 for Treatment of Metastatic Adenocarcinoma of the Pancreas
A Phase I and Randomized Phase II Study of Nab-Paclitaxel/Gemcitabine With or Without AZD1775 for Treatment of Metastatic Adenocarcinoma of the Pancreas
Enrollment Status: Completed
Publish Date: April 25, 2023
Intervention Type: Drug
Study Drugs: Adavosertib, Gemcitabine hydrochloride, Nab-paclitaxel
Study Phase: Phase 1/Phase 2
Preoperative Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the Pancreas
Preoperative Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the Pancreas
Enrollment Status: Unknown
Publish Date: May 24, 2022
Intervention Type: Drug, Procedure, Radiation
Study Drugs: mFOLFIRINOX, FOLFOX
Study Phase: Phase 2
A Phase 1b Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancer
A Phase 1b Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancer
Enrollment Status: Completed
Publish Date: September 09, 2020
Intervention Type: Drug
Study Phase: Phase 1
A Phase I/II, Open-Label Study to Investigate the Safety, Clinical Activity, Pharmacokinetics, and Pharmacodynamics of GSK3145095 Administered Alone and in Combination With Anticancer Agents Including Pembrolizumab in Adult Participants With Selected Advanced Solid Tumors
A Phase I/II, Open-Label Study to Investigate the Safety, Clinical Activity, Pharmacokinetics, and Pharmacodynamics of GSK3145095 Administered Alone and in Combination With Anticancer Agents Including Pembrolizumab in Adult Participants With Selected Advanced Solid Tumors
Enrollment Status: Terminated
Publish Date: July 31, 2020
Intervention Type: Drug
Study Phase: Phase 2
Improving the Approach to and Management of the Older Metastatic Breast Cancer Patient Via a Provider Didactic Intervention
Improving the Approach to and Management of the Older Metastatic Breast Cancer Patient Via a Provider Didactic Intervention
Enrollment Status: Completed
Publish Date: March 02, 2020
Intervention Type: Behavioral
Study Phase: Not Applicable
Phase I Study of Drug-Eluting Irinotecan Beads (DEBIRI) in Refractory Metastatic Colorectal Cancer With Liver-Only or Liver-Predominant Disease
Phase I Study of Drug-Eluting Irinotecan Beads (DEBIRI) in Refractory Metastatic Colorectal Cancer With Liver-Only or Liver-Predominant Disease
Enrollment Status: Terminated
Publish Date: February 26, 2018
Intervention Type: Procedure, Combination product
Study Phase: Phase 1
View 13 Less Clinical Trials

95 Total Publications

Prioritizing Benefit Over Tolerance Among Older Adults With Pancreatic Cancer.
Prioritizing Benefit Over Tolerance Among Older Adults With Pancreatic Cancer.
Journal: JCO oncology practice
Published: December 15, 2025
View All 95 Publications
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Baltimore, MD 
 (55.5 miles away)
410-955-8964
Languages Spoken:
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See accepted insurances
Offers Telehealth

Dr. Mark Yarchoan is a physician–scientist based in Baltimore who specializes in the treatment and study of gastrointestinal cancers, with a particular focus on liver malignancies, including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). He received his undergraduate degree from Amherst College and his medical degree from the Perelman School of Medicine at the University of Pennsylvania. He completed his residency in internal medicine at the Hospital of the University of Pennsylvania, followed by a fellowship in medical oncology at the Johns Hopkins University School of Medicine, where he joined the faculty in 2018. Dr. Yarchoan leads a research laboratory dedicated to developing novel immunotherapies for liver cancers. His translational research program integrates analyses of clinical trial biospecimens with preclinical modeling to identify and overcome barriers to effective antitumor immunity. A major focus of his work is the development of therapeutic cancer vaccines for hepatobiliary malignancies. He serves as Principal Investigator on multiple clinical trials for hepatobiliary cancers, contributes to international guideline committees for liver cancer, and is a member of the Johns Hopkins Graduate Training Programs in Cellular and Molecular Medicine and Immunology. Dr. Yarchoan’s contributions have been recognized with numerous honors, including the ASCO Young Investigator Award, the Conquer Cancer Foundation Career Development Award, the Mark R. Clements Award from the Cholangiocarcinoma Foundation, and the Blue Faery Award for Excellence in Liver Cancer Research. Dr. Yarchoan is rated as a Distinguished provider by MediFind in the treatment of Cholangiocarcinoma (Bile Duct Cancer). His top areas of expertise are Fibrolamellar Carcinoma, Cholangiocarcinoma (Bile Duct Cancer), Liver Cancer, Pancreatic Cancer, and Hepatectomy.

Distinguished in Cholangiocarcinoma (Bile Duct Cancer)
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 (62.1 miles away)
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Thomas Karasic is a Hematologist Oncology specialist and a Hematologist in Philadelphia, Pennsylvania. Dr. Karasic is rated as a Distinguished provider by MediFind in the treatment of Cholangiocarcinoma (Bile Duct Cancer). His top areas of expertise are Cholangiocarcinoma (Bile Duct Cancer), Pancreatic Cancer, Colorectal Cancer, Fibrolamellar Carcinoma, and Tissue Biopsy.

VIEW MORE CHOLANGIOCARCINOMA (BILE DUCT CANCER) DOCTORS

Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

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Find Dr. Dotan's expertise for a condition
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  • Elite
  • Colorectal Cancer
    Dr. Dotan is
    Elite
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  • Pancreatic Cancer
    Dr. Dotan is
    Elite
    . Learn about Pancreatic Cancer.
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  • Distinguished
  • Anal Cancer
    Dr. Dotan is
    Distinguished
    . Learn about Anal Cancer.
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  • Cholangiocarcinoma (Bile Duct Cancer)
    Dr. Dotan is
    Distinguished
    . Learn about Cholangiocarcinoma (Bile Duct Cancer).
    See more Cholangiocarcinoma (Bile Duct Cancer) experts
  • Familial Colorectal Cancer
    Dr. Dotan is
    Distinguished
    . Learn about Familial Colorectal Cancer.
    See more Familial Colorectal Cancer experts
  • Familial Pancreatic Cancer
    Dr. Dotan is
    Distinguished
    . Learn about Familial Pancreatic Cancer.
    See more Familial Pancreatic Cancer experts
  • Gastroesophageal Junction Cancer
    Dr. Dotan is
    Distinguished
    . Learn about Gastroesophageal Junction Cancer.
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  • Lynch Syndrome
    Dr. Dotan is
    Distinguished
    . Learn about Lynch Syndrome.
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View All 8 Distinguished Conditions
  • Advanced
  • Appendix Cancer
    Dr. Dotan is
    Advanced
    . Learn about Appendix Cancer.
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  • Fibrolamellar Carcinoma
    Dr. Dotan is
    Advanced
    . Learn about Fibrolamellar Carcinoma.
    See more Fibrolamellar Carcinoma experts
  • Gallbladder Adenocarcinoma
    Dr. Dotan is
    Advanced
    . Learn about Gallbladder Adenocarcinoma.
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  • Gallbladder Cancer
    Dr. Dotan is
    Advanced
    . Learn about Gallbladder Cancer.
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  • Experienced
  • Ampullary Cancer
    Dr. Dotan is
    Experienced
    . Learn about Ampullary Cancer.
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  • Angiosarcoma
    Dr. Dotan is
    Experienced
    . Learn about Angiosarcoma.
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  • Biliary Dyskinesia
    Dr. Dotan is
    Experienced
    . Learn about Biliary Dyskinesia.
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  • Breast Cancer
    Dr. Dotan is
    Experienced
    . Learn about Breast Cancer.
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  • Esophageal Cancer
    Dr. Dotan is
    Experienced
    . Learn about Esophageal Cancer.
    See more Esophageal Cancer experts
  • Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET)
    Dr. Dotan is
    Experienced
    . Learn about Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET).
    See more Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) experts
View All 16 Experienced Conditions
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