Evidence-based Modeling for Acquired Dyslexia Treatments
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.
• Fluent in English as a first language pre-stroke by self report.
• Normal or corrected-to-normal vision.
• Normal or aided hearing.
• Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).
• Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III.