Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of this study is to prospectively collect specimens from pediatric patients with diffuse intrinsic pontine glioma or brainstem glioma, either during therapy or at autopsy, in order to characterize the molecular abnormalities of this tumor.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 21
Healthy Volunteers: f
View:
• Patients of any age with clinical and radiologic diagnosis of diffuse intrinsic pontine glioma
• Patients with other high-grade gliomas originating in the brainstem
• Patients with focal gliomas (WHO grade I/II) of the brainstem
Locations
United States
Washington, D.c.
Children's National Medical Center
RECRUITING
Washington D.c.
Contact Information
Primary
Javad Nazarian, PhD
JNazarian@cnmc.org
202-476-6022
Backup
Caroline Kopsidas, BS
ckopsidas@childrensnational.org
240-393-3359
Time Frame
Start Date: 2010-04
Estimated Completion Date: 2030-04
Participants
Target number of participants: 100
Treatments
Patient samples
Fresh-frozen and fixed tumor samples, correspondent normal brain tissue samples, cerebrospinal fluid, urine, and serum samples from patients affected with diffuse intrinsic pontine glioma or brainstem glioma
Related Therapeutic Areas
Sponsors
Leads: Children's National Research Institute