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Evaluation of the Effectiveness of Patient-Specific 3D-Printed Titanium Facial Implants in the Reconstruction and Aesthetic Correction of Facial Defects: A Clinical Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects. The study will include patients presenting with congenital, traumatic, or post-surgical facial deformities requiring reconstructive intervention. Eligible participants will undergo preoperative clinical assessment and radiological imaging to design customized implants using computer-aided design (CAD) and 3D printing technology. The implants will be fabricated from medical-grade titanium and surgically placed according to standardized maxillofacial reconstructive protocols. Postoperative follow-up will assess functional outcomes, implant stability, complication rates, and aesthetic improvement over a defined observation period. Outcome evaluation will include clinical examination and patient-reported satisfaction measures. The objective of this study is to determine whether patient-specific 3D-printed titanium implants provide reliable functional restoration and improved aesthetic outcomes in facial reconstruction compared to conventional reconstructive techniques.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Age 18 years or older.

• Presence of facial bone defects resulting from cystic or tumoral osteolytic lesions.

• Acquired or congenital facial deformities associated with bony defects or facial asymmetry.

• Patients requiring patient-specific 3D-printed titanium implants for maxillofacial reconstruction.

• Aesthetic indications requiring custom facial implant design, including microgenia (chin retrusion).

• Ability to provide written informed consent.

Locations
Other Locations
Syrian Arab Republic
Ahmad Fayez Ahmad
RECRUITING
Latakia
Contact Information
Primary
Ahmad F Ahmad, Phd
ahmad.fayez.ahmad@latakia-univ.edu.sy
00963992035690
Time Frame
Start Date: 2026-04-26
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 30
Treatments
Experimental: Patient-Specific 3D-Printed Titanium Implant Reconstruction Group
Participants in this study will undergo reconstruction of facial defects using patient-specific three-dimensional (3D)-printed titanium implants. Preoperative planning will be performed using clinical assessment and high-resolution radiographic imaging to design customized implants tailored to each patient's anatomical defect. The implants will be fabricated from medical-grade titanium using additive manufacturing technology.~Surgical reconstruction will be performed under standard maxillofacial surgical protocols. The customized titanium implants will be positioned and fixed to restore both functional integrity and facial aesthetics. Postoperative follow-up will include clinical evaluation, radiographic assessment, and monitoring for complications, implant stability, and aesthetic outcomes over the defined study period.
Sponsors
Leads: Tishreen University

This content was sourced from clinicaltrials.gov