Stroke Clinical Trials

Find Stroke Clinical Trials Near You

Can Pre-operative Lean Mass Predict Weight Loss After Roux-en-Y Gastric Bypass?

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to evaluate whether preoperative fat-free mass predicts post-operative weight loss in patients undergoing Roux-En-Y gastric bypass. The primary objective of this study is to evaluate whether preoperative fat-free mass predicts weight loss in the two years following RYGB. The investigators will collect the following data, assessed as part of routine follow-up: * height, weight, hip and waist circumferences * body composition by bioimpedance analysis and dual energy-X-ray absorptiometry * Muscle strength and physical activity * Nutritional parameters: resting energy expenditure, eating behavior and digestive tolerance, plasma micronutrient status. . * Cardiovascular risk factors: fasting glucose, blood levels of Hb1Ac, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood pressure * Co-morbidities: joint pain and arthritis, sleep apnea, gastro-oesophageal reflux, metabolic dysfunction-associated fatty liver disease (MAFLD), cancer, stroke, heart attack. Quality of life: quality of life by the Bariatric Analysis and Reporting Outcome (BAROS) questionnaire, symptoms of dumping syndrome by the Sigstad diagnostic score system Birthdate, birthweight and term of their children

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Patients ≥ 18 years AND

• Meeting inclusion criteria for RYGB (www.smob.ch): BMI ≥35 kg/m2, failure of weight-reducing programs over 2 years (for patients with a BMI ≥50 kg/m2, 1 year), understanding of the necessity to change the lifestyle and eating habits post-operatively, signed consent for lifelong post-operative follow-up in a recognized bariatric center AND

• Scheduled RYGB at the HUG OR previous RYGB at the HUG with a present follow-up in Clinical Nutrition and dietetics at the HUG AND

• Understanding French

Locations
Other Locations
Switzerland
Geneva University Hospitals
RECRUITING
Geneva
Contact Information
Primary
Laurence Genton, MD
laurence.genton@hug.ch
0041 79 553 34 84
Backup
Laure Wilmart-Beck
laure.wilmart@hug.ch
0041 22 372 93 49
Time Frame
Start Date: 2025-08-18
Estimated Completion Date: 2032-08-18
Participants
Target number of participants: 91
Treatments
Patients with scheduled RYGB at the Geneva University Hospitals
Morbidly obese patients scheduled for Roux-en-Y gastric bypass
Sponsors
Leads: University Hospital, Geneva

This content was sourced from clinicaltrials.gov