Experienced in WT1-Related Wilms Tumor Syndromes

Dr. William J. Charles

Oncology | Hematology
Duke Health
Duke Health Lake Norman Hospital
171 Fairview Rd, 
Mooresville, NC 
On Staff At
Clinical Trials:Currently Recruiting for 1 Trial
Offers Telehealth
37 Years of Experience

Experienced in WT1-Related Wilms Tumor Syndromes
Duke Health
Duke Health Lake Norman Hospital
171 Fairview Rd, 
Mooresville, NC 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

William Charles is an Oncologist and a Hematologist in Mooresville, North Carolina. Dr. Charles has been practicing medicine for over 37 years and is rated as an Experienced provider by MediFind in the treatment of WT1-Related Wilms Tumor Syndromes. His top areas of expertise are Lung Cancer, Familial Colorectal Cancer, Pleuropulmonary Blastoma, and Colorectal Cancer.

His clinical research consists of participating in 11 clinical trials. MediFind looks at clinical research from the past 15 years.

Graduate Institution
Ross University, 1988
Specialties
Oncology
Hematology
Licenses
Internal Medicine in NC
Board Certifications
American Board Of Internal Medicine, Internal Medicine
Fellowships
Hematology and Medical Oncology, Maimonides Medical Center, Hematology and Medical Oncology, Brookdale University Hospital Medical Center
Hospital Affiliations
Novant Health Mint Hill Medical Center
Novant Health Huntersville Medical Center
Novant Health Presbyterian Medical Center
Languages Spoken
English
Gender
Male

Insurance

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Aetna
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Locations

Duke Health Lake Norman Hospital
171 Fairview Rd, Mooresville, NC 28117
Call: 704-660-4000

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


11 Clinical Trials

A Randomized Phase III Trial for Surgically Resected Early Stage Non-small Cell Lung Cancer: Crizotinib Versus Observation for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein
A Randomized Phase III Trial for Surgically Resected Early Stage Non-small Cell Lung Cancer: Crizotinib Versus Observation for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein
Enrollment Status: Recruiting
Publish Date: July 03, 2024
Intervention Type: Other, Drug
Study Drug: Crizotinib
Study Phase: Phase 3
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Enrollment Status: Active_not_recruiting
Publish Date: October 06, 2025
Intervention Type: Other, Procedure, Biological, Drug
Study Phase: Not Applicable
Randomized Study of Erlotinib Vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)
Randomized Study of Erlotinib Vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)
Enrollment Status: Active_not_recruiting
Publish Date: September 22, 2025
Intervention Type: Other, Drug
Study Drug: Erlotinib Hydrochloride
Study Phase: Phase 3
Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)-A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)-A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
Enrollment Status: Active_not_recruiting
Publish Date: September 22, 2025
Intervention Type: Procedure, Biological, Other
Study Drug: Nivolumab
Study Phase: Phase 3
A Randomized, Open-Label, Phase 3 Study of Abemaciclib Combined With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone in Patients With High Risk, Node Positive, Early Stage, Hormone Receptor Positive, Human Epidermal Receptor 2 Negative, Breast Cancer
A Randomized, Open-Label, Phase 3 Study of Abemaciclib Combined With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone in Patients With High Risk, Node Positive, Early Stage, Hormone Receptor Positive, Human Epidermal Receptor 2 Negative, Breast Cancer
Enrollment Status: Active_not_recruiting
Publish Date: April 20, 2025
Intervention Type: Drug
Study Drugs: Abemaciclib, Standard Adjuvant Endocrine Therapy
Study Phase: Phase 3
A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients With Stage 0-III Colon or Rectal Cancer, Phase III - Preventing Adenomas of the Colon With Eflornithine and Sulindac (PACES)
A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients With Stage 0-III Colon or Rectal Cancer, Phase III - Preventing Adenomas of the Colon With Eflornithine and Sulindac (PACES)
Enrollment Status: Active_not_recruiting
Publish Date: March 30, 2025
Intervention Type: Drug
Study Phase: Phase 3
Randomized Double-Blind Placebo Controlled Study of Testosterone in the Adjuvant Treatment of Postmenopausal Women With Aromatase Inhibitor Induced Arthralgias
Randomized Double-Blind Placebo Controlled Study of Testosterone in the Adjuvant Treatment of Postmenopausal Women With Aromatase Inhibitor Induced Arthralgias
Enrollment Status: Completed
Publish Date: January 28, 2025
Intervention Type: Other, Drug
Study Phase: Phase 3
Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer
Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer
Enrollment Status: Active_not_recruiting
Publish Date: January 13, 2025
Intervention Type: Other
Study Phase: Phase 3
Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients With High-Risk, Hormone Receptor-Positive and HER2/Neu Negative Breast Cancer
Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients With High-Risk, Hormone Receptor-Positive and HER2/Neu Negative Breast Cancer
Enrollment Status: Active_not_recruiting
Publish Date: December 27, 2024
Intervention Type: Drug, Other
Study Drugs: Anastrozole, Everolimus, Exemestane, Goserelin Acetate, Letrozole, Leuprolide Acetate, Tamoxifen Citrate
Study Phase: Phase 3
A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial
A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial
Enrollment Status: Terminated
Publish Date: April 05, 2023
Intervention Type: Other, Drug
Study Drug: Aspirin
Study Phase: Phase 3
A 2-Arm Phase 2 Double-Blind Randomized Study of Carboplatin, Pemetrexed Plus Placebo Versus Carboplatin, Pemetrexed Plus Truncated Demcizumab as First-Line Treatment in Subjects With Stage IV Non-Squamous Non-Small Cell Lung Cancer
A 2-Arm Phase 2 Double-Blind Randomized Study of Carboplatin, Pemetrexed Plus Placebo Versus Carboplatin, Pemetrexed Plus Truncated Demcizumab as First-Line Treatment in Subjects With Stage IV Non-Squamous Non-Small Cell Lung Cancer
Enrollment Status: Completed
Publish Date: September 09, 2020
Intervention Type: Drug
Study Phase: Phase 2
View 10 Less Clinical Trials
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VIEW MORE WT1-RELATED WILMS TUMOR SYNDROMES DOCTORS

Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

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Find Dr. Charles's expertise for a condition
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    • Distinguished
    • Colorectal Cancer
      Dr. Charles is
      Distinguished
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    • Familial Colorectal Cancer
      Dr. Charles is
      Distinguished
      . Learn about Familial Colorectal Cancer.
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    • Lung Cancer
      Dr. Charles is
      Distinguished
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    • Pleuropulmonary Blastoma
      Dr. Charles is
      Distinguished
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    • Small Cell Lung Cancer (SCLC)
      Dr. Charles is
      Distinguished
      . Learn about Small Cell Lung Cancer (SCLC).
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    • Advanced
    • ALK-Positive Non-Small Cell Lung Cancer
      Dr. Charles is
      Advanced
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    • Anemia
      Dr. Charles is
      Advanced
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    • Breast Cancer
      Dr. Charles is
      Advanced
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    • EGFR Positive Lung Cancer
      Dr. Charles is
      Advanced
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    • Inflammatory Breast Cancer
      Dr. Charles is
      Advanced
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    • Large-Cell Immunoblastic Lymphoma
      Dr. Charles is
      Advanced
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    View All 21 Advanced Conditions
    • Experienced
    • Acute Eosinophilic Pneumonia
      Dr. Charles is
      Experienced
      . Learn about Acute Eosinophilic Pneumonia.
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    • Acute Myeloblastic Leukemia with Maturation
      Dr. Charles is
      Experienced
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    • Acute Myeloblastic Leukemia without Maturation
      Dr. Charles is
      Experienced
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    • Acute Myeloid Leukemia (AML)
      Dr. Charles is
      Experienced
      . Learn about Acute Myeloid Leukemia (AML).
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    • Adult Immune Thrombocytopenia
      Dr. Charles is
      Experienced
      . Learn about Adult Immune Thrombocytopenia.
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    • Adult Soft Tissue Sarcoma
      Dr. Charles is
      Experienced
      . Learn about Adult Soft Tissue Sarcoma.
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    View All 60 Experienced Conditions
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