Dr. Maheswari Senthil

Dr. Maheswari Senthil is a board-certified UCI health surgical oncologist who specializes in the management of gastric cancer, peritoneal malignancies and advanced abdominal cancers and retroperitoneal sarcomas.An internationally recognized surgical leader in the management of peritoneal carcinomatosis, she offers leading-edge clinical trials that span the breadth of intraperitoneal chemotherapy, novel diagnostic approaches and cytoreduction surgery with heated intraperitoneal chemotherapy. She is the principal investigator of EA 2234 STOPGAP II trial, a national randomized controlled trial for patients with gastric carcinomatosis, investigating the survival benefits of normothermic intraperitoneal paclitaxel combined with systemic therapy.Senthil earned her medical degree at Madurai Medical college in Tamilnadu, India, graduating in the top one percent of her class. She completed a residency in general surgery at Rutger's University in New Jersey and a fellowship in surgical oncology at City of Hope in Duarte, Calif. She is the Chief of the Division of Surgical Oncology and the Director of the Peritoneal Malignancy Program at UC Irvine School of Medicine.Her research interests include design of treatment and diagnostic clinical trials to test treatment approaches for managing advanced cancers. She also is studying a novel-exosome-based liquid biopsy for detection of peritoneal carcinomatosis and a peritoneal carcinomatosis tumor model to design new treatment approaches. She is the medical director of the Institute of Clinical and Translational Science and supports investigators as they develop new biomarkers for early cancer detection.Through bedside to bench to bedside translational research and technical excellence, Senthil seeks to improve diagnosis and treatment of patients with advanced cancers. Her focus is on healing the body as well as the mind and spirit.Nickname: Magi.

Dr. Senthil is highly rated in 8 conditions, according to our data. Her clinical expertise encompasses Colorectal Cancer, Pseudomyxoma Peritonei, Breast Cancer, Pancreaticoduodenectomy, and Gastrostomy.

Dr. Senthil is board certified in American Board Of Surgery - Surgery (General Surgery). She is actively involved in clinical research, co-authoring 94 peer reviewed articles and participating in 1 clinical trial.