Overview
Nicholas Maragakis treats patients with motor neuron diseases, such as amyotrophic lateral sclerosis (ALS). This care is coordinated with the Johns Hopkins Center for ALS Specialty Care, a multidisciplinary clinic with expertise in treating patients with ALS and providing support to their caregivers. He serves as medical director of the ALS Clinical Trials Unit, an extension of the multidisciplinary clinic that seeks to facilitate opportunities for patients with ALS to participate in clinical trials that could advance the treatment of this disease. Dr. Maragakis is interested in the basic science of understanding neurodegenerative diseases, as well as the translational potential of therapeutic compounds developed in the laboratory. His fundamental research interest is in using stem cells — more specifically, stem cell-derived motor neurons and glia — for understanding the development and propagation of ALS. His laboratory has been involved in creating and characterizing lines of stem cells from patients with ALS using induced pluripotent stem cell (iPSC) methodologies. The laboratory has a large library of iPSCs from patients with familial ALS and from patients with sporadic ALS. The utilization of this library of iPSCs has facilitated the development of a spinal cord-specific iPSC-astrocyte/motor neuron co-culture system, which has been leveraged for the development of assays that can be used for both the basic understanding of ALS astrocyte and motor neuron biology as well as, eventually, drug screening for ALS therapeutics. His laboratory has taken its long-standing interests in astrocyte biology, as it relates to ALS, to develop a program that investigates astrocyte-specific mechanisms as contributors to the progression (both temporally and anatomically) of disease in ALS. In this vein, there is an interest in astrocytic glutamate transporters and, more recently, astrocyte hemichannels and gap junctions.
Dr. Maragakis is highly rated in 1 condition, according to our data. His clinical expertise encompasses 15q11.2 Microdeletion, Sandhoff Disease, Foot Drop, and Pseudobulbar Affect.
He is actively involved in clinical research, co-authoring 114 peer reviewed articles and participating in 3 clinical trials. Dr. Maragakis is currently accepting new patients.
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Locations
601 North Caroline Street, Floor 5, Floor 5, Baltimore, MD 21287
Clinical Research
Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.
3 Clinical Trials
Johns Hopkins Bayview Medical Center
Andrew Mammen is a Neuromusculoskeletal Medicine specialist and a Neurologist practicing medicine in Baltimore, Maryland. Dr. Mammen is highly rated in 10 conditions, according to our data. His clinical expertise encompasses Myositis, Polymyositis, Dermatomyositis, and Necrotizing Myopathy (NM). Dr. Mammen is board certified in American Board Of Psychiatry And Neurology. Dr. Mammen is currently accepting new patients.
Johns Hopkins Outpatient Center
Arens Taga is a neurologist specializing in neuromuscular diseases, with a particular focus on amyotrophic lateral sclerosis (ALS) and other motor neuron diseases. His clinical work aims to improve the quality of care for patients with ALS through biomarker-based, precision medicine approaches that refine disease stratification and facilitate more targeted and efficient enrollment in clinical trials. As a clinician-scientist, Dr. Taga uses patient-derived induced pluripotent stem cells to model ALS, uncover novel disease mechanisms and identify therapeutic targets that are translatable to clinical trials. In recognition of his work in ALS, Dr. Taga was awarded the 2025 Richard Olney Clinician Scientist Development Award, which honors early-career physician-scientists dedicated to advancing ALS research. Dr. Taga earned his medical degree from the School of Medicine and Surgery at the University of Parma, Italy, where he also completed his neurology residency. He subsequently trained at The Johns Hopkins University, completing a postdoctoral research fellowship in the neuromuscular division, an internal medicine internship, a neurology residency and a neuromuscular clinical fellowship. Dr. Taga is highly rated in 6 conditions, according to our data. His clinical expertise encompasses 15q11.2 Microdeletion, Primary Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease), and Cluster Headache. Dr. Taga is board certified in American Board Of Psychiatry And Neurology.
Peds Neurology PSB
Neil Porter is a Neuromusculoskeletal Medicine specialist and a Neurologist practicing medicine in Baltimore, Maryland. Dr. Porter is highly rated in 29 conditions, according to our data. His clinical expertise encompasses Myasthenia Gravis, Mononeuritis Multiplex, Multiple Mononeuropathy, Riboflavin Transporter Deficiency Neuronopathy, and Gastrostomy. Dr. Porter is board certified in American Board Of Psychiatry And Neurology - Clinical Neurophysiology, 1997 and American Board Of Psychiatry And Neurology - Neurology, 1996. Dr. Porter is currently accepting new patients.
Frequently Asked Questions about Dr. Nicholas J. Maragakis
How do I make an appointment with Dr. Nicholas J. Maragakis?
You can book an appointment with Dr. Nicholas J. Maragakis by calling their office at 410-955-9441. MediFind provides direct contact information so you can schedule visits, second opinions, or consultations without navigating third-party calendars.
Is Dr. Nicholas J. Maragakis a top-rated expert for 15q11.2 Microdeletion?
MediFind is an objective health platform that identifies experts based on real-world data. Dr. Nicholas J. Maragakis is classified as an Elite expert for 15q11.2 Microdeletion, meaning they are among the top experts in the country for this condition. This ranking is based on their volume of patients, published research, and peer connections.
What conditions does Dr. Nicholas J. Maragakis specialize in?
While Dr. Nicholas J. Maragakis is a Neuromusculoskeletal Medicine, they have specific expertise in 15q11.2 Microdeletion, Sandhoff Disease, and Foot Drop. MediFind analyzes a doctor's articles and referral patterns to identify their specific areas of focus within Neuromusculoskeletal Medicine.
Does Dr. Nicholas J. Maragakis participate in research or clinical trials?
Yes. Dr. Nicholas J. Maragakis has published 114 articles and abstracts on conditions like 15q11.2 Microdeletion. You can view a list of Dr. Nicholas J. Maragakis's latest peer-reviewed publications and clinical trial participation on their profile to see if they are active in new treatments.
Does Dr. Nicholas J. Maragakis accept my insurance?
Dr. Nicholas J. Maragakis accepts most major insurance plans, including Aetna and Anthem BCBS. We recommend calling the office directly at 410-955-9441 to verify that your specific plan is currently accepted before your visit.
Areas of Expertise
MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.
Learn more about MediFind’s expert tiers
- Elite
- 15q11.2 MicrodeletionDr. Maragakis isElite. Learn about 15q11.2 Microdeletion.
- Experienced
- Foot DropDr. Maragakis isExperienced. Learn about Foot Drop.
- Pseudobulbar AffectDr. Maragakis isExperienced. Learn about Pseudobulbar Affect.
- Sandhoff DiseaseDr. Maragakis isExperienced. Learn about Sandhoff Disease.