Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 85
Healthy Volunteers: t
View:

• Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.

• Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).

• Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.

Locations
United States
Oregon
Casey Eye Institute - Oregon Health & Science University
RECRUITING
Portland
Contact Information
Primary
Humberto Martinez, COT, MBA
martinhu@ohsu.edu
503-494-7712
Backup
Denzil Romfh, OD
romfhd@ohsu.edu
503-494-4351
Time Frame
Start Date: 2024-09-01
Estimated Completion Date: 2026-12
Participants
Target number of participants: 125
Treatments
Uveitis Group
Eyes with active inflammation due to various systemic diseases
Posterior Vitreous Detachment Group
Eyes with vitreous floaters and posterior vitreous detachment
Healthy/Control Group
Healthy eyes with no history of uveitis, posterior vitreous detachment, or previous eye surgery
Sponsors
Collaborators: National Eye Institute (NEI)
Leads: Oregon Health and Science University

This content was sourced from clinicaltrials.gov