Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive Therapy (DECLAM).

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

Neutropenia after induction or consolidation therapy for acute myeloid leukemia (AML) patients is associated with a high morbi-mortality rates, especially due to infectious complications. These are managed according to international recommandations (ECIL and IDSA) with antibiotherapy and antifungal strategy. Although the patients suffer of digestive symptoms, intestinale complications are really less explored. Neutropenic enterocolitis (NE), cytomegalovirus (CMV) colitis, Clostridium difficile colitis, specific lesion, ischemic colitis are not well-known. No prospective study evaluate NE and these digestive complications which have high morbi-mortality rates.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age \> 18 years

• inclusion criteria:

⁃ Every patient of hematology:

• Able to receive an intensive treatment for AML (induction then intensive consolidations) causing a neutropenia with high infectious risk

• In state to give its consent

• Affiliated to a social security system

Locations
Other Locations
France
CHU Amiens-Picardie
NOT_YET_RECRUITING
Amiens
CHU de Caen
NOT_YET_RECRUITING
Caen
Henri Becquerel Center
RECRUITING
Rouen
Contact Information
Primary
Delphine LEBON, Doctor
lebon.delphine@chu-amiens.fr
0033 3 22 45 59 17
Time Frame
Start Date: 2019-01-14
Estimated Completion Date: 2024-11-13
Participants
Target number of participants: 170
Sponsors
Leads: Centre Hospitalier Universitaire, Amiens

This content was sourced from clinicaltrials.gov