Paul E. Sax
Elite in HIV/AIDS

Dr. Paul E. Sax

Infectious Disease | Internal Medicine
Mass General Brigham
Brigham And Womens Physicians Organization Inc
75 Francis St, 
Boston, MA 
Offers Telehealth
36 Years of Experience

Elite in HIV/AIDS
Mass General Brigham
Brigham And Womens Physicians Organization Inc
75 Francis St, 
Boston, MA 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

Dr. Paul E. Sax is Clinical Director of the Division of Infectious Diseases at Brigham and Women's Hospital (BWH), where he holds the Bruce and Robert Beal Distinguished Chair, and Professor of Medicine at Harvard Medical School. Dr. Sax received his MD from Harvard Medical School, did his residency in Internal Medicine at BWH, then fellowship in Infectious Diseases at Massachusetts General Hospital.He is Editor-in-Chief of Open Forum Infectious Diseases, is Section Editor of HIV/AIDS in UpToDate, on the Editorial Board of NEJM Journal Watch Infectious Diseases (where he writes the HIV and ID Observations blog), and on the editorial advisory board of Medscape HIV/AIDS. Dr. Sax is the Associate Program Director for the Mass General Brigham fellowship in Infectious Diseases, is on the core faculty of the International Antiviral Society – USA, and teaches regularly on HIV and infectious diseases locally, nationally, and internationally. In addition to his clinical practice and teaching, Dr. Sax’s ongoing areas of research include clinical trials of antiretroviral therapies, cost-effectiveness of management strategies for HIV, and toxicity of antiretroviral therapy. He is presently the principal investigator at the BWH AIDS Clinical Trials Unit, and is a member of the Cost-Effectiveness of Preventing AIDS Complications (CEPAC) Research Group.

Dr. Sax is rated as an Elite provider by MediFind in the treatment of HIV/AIDS. His top areas of expertise are HIV/AIDS, Nontuberculous Mycobacterial Lung Disease, Myelitis, and AIDS Dementia Complex.

His clinical research consists of co-authoring 201 peer reviewed articles and participating in 11 clinical trials. MediFind looks at clinical research from the past 15 years. In particular, he has co-authored 125 articles and participated in 4 clinical trials in the study of HIV/AIDS.

Graduate Institution
Harvard Medical School, 1987
Residency
Brigham and Women's Hospital, 1987 - 1990
Specialties
Infectious Disease
Internal Medicine
Licenses
Internal Medicine in MA
Board Certifications
Internal Medicine
Infectious Disease
Fellowships
Massachusetts General Hospital, 1990 - 1992
Hospital Affiliations
Brigham And Women's Hospital
Languages Spoken
English
Gender
Male
Awards
Boston Magazine Top Doctor
2022
Castle Connolly America's Top Doctors
2022

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
Anthem
  • EPO
  • HMO
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Blue Cross Blue Shield
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  • PPO
Blue Shield of California
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  • OTHER MEDICARE
  • OTHER MEDICARE PART D
  • PPO
BMC HealthNet
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  • MEDICARE SNP
Cigna
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Health Net

Accepted plan types not found. Please verify directly with the provider.

Humana
  • HMO
  • INDEMNITY
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  • PPO
Managed Medicaid
  • OTHER MANAGED MEDICAID
Mass General Brigham Health Plan
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • PPO
Medicaid
  • OTHER MEDICAID
  • STATE MEDICAID
Tufts
  • HMO
UnitedHealthcare
  • EPO
  • HMO
  • POS
  • PPO
Wellcare
  • EPO
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
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  • OTHER MEDICARE
  • OTHER MEDICARE PART D
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Locations

BRIGHAM AND WOMENS PHYSICIANS ORGANIZATION INC
75 Francis St, Boston, MA 02115
Call: 617-732-5500

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


11 Clinical Trials

Effect of Antiretroviral Treatment Initiated During Acute HIV-1 Infection on Measures of HIV-1 Persistence and on HIV-1-Specific Immune Responses
Effect of Antiretroviral Treatment Initiated During Acute HIV-1 Infection on Measures of HIV-1 Persistence and on HIV-1-Specific Immune Responses
Enrollment Status: Completed
Publish Date: August 29, 2025
Intervention Type: Drug
Study Drug: Elvitegravir+Cobicistat+Emtricitabine+Tenofovir alafenamide or other medically-appropriate FDA-approved antiretroviral therapy
Study Phase: Phase 2
Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide (The Do IT Study)
Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide (The Do IT Study)
Enrollment Status: Completed
Publish Date: July 02, 2025
Intervention Type: Drug
Study Drugs: Doravirine, Tenofovir alafenamide, Emtricitabine, Lamivudine, Integrase strand transfer inhibitors, Tenofovir disproxil fumarate
Study Phase: Phase 4
Identification of Biomarkers to Predict Time to Plasma HIV RNA Rebound and Post-Treatment Viral Control During an Intensively Monitored Antiretroviral Pause (IMAP)
Identification of Biomarkers to Predict Time to Plasma HIV RNA Rebound and Post-Treatment Viral Control During an Intensively Monitored Antiretroviral Pause (IMAP)
Enrollment Status: Completed
Publish Date: December 13, 2024
Intervention Type: Drug
Pitavastatin to REduce Physical Function Impairment and FRailty in HIV (PREPARE)
Pitavastatin to REduce Physical Function Impairment and FRailty in HIV (PREPARE)
Enrollment Status: Completed
Publish Date: October 28, 2024
Intervention Type: Drug
Study Phase: Phase 3
A Phase IIIb, Randomized, Multicenter, Active-controlled, Parallel-group, Non-inferiority, Open-label Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine Administered Every Two Months From a Bictegravir/Emtricitabine/Tenofovir Alafenamide Single Tablet Regimen in HIV-1 Infected Adults Who Are Virologically Suppressed
A Phase IIIb, Randomized, Multicenter, Active-controlled, Parallel-group, Non-inferiority, Open-label Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine Administered Every Two Months From a Bictegravir/Emtricitabine/Tenofovir Alafenamide Single Tablet Regimen in HIV-1 Infected Adults Who Are Virologically Suppressed
Enrollment Status: Completed
Publish Date: June 04, 2024
Intervention Type: Drug
Study Drugs: Cabotegravir, Rilpivirine, BIKTARVY
Study Phase: Phase 3
A Single-arm Study to Evaluate the Feasibility and Efficacy of a Minimal Monitoring Strategy to Deliver Pan-genotypic Ribavirin-free HCV Therapy to HCV Infected Populations Who Are HCV Treatment Naïve With Evidence of Active HCV Infection: The MINMON Study
A Single-arm Study to Evaluate the Feasibility and Efficacy of a Minimal Monitoring Strategy to Deliver Pan-genotypic Ribavirin-free HCV Therapy to HCV Infected Populations Who Are HCV Treatment Naïve With Evidence of Active HCV Infection: The MINMON Study
Enrollment Status: Completed
Publish Date: February 04, 2022
Intervention Type: Drug, Other
Study Phase: Phase 4
Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy
Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy
Enrollment Status: Completed
Publish Date: August 03, 2021
Intervention Type: Drug
Study Phase: Phase 1/Phase 2
Safety, Tolerability, and Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome and Immune Activation Markers in HIV-Infected Participants on Suppressive Antiretroviral Therapy: A Phase II Study
Safety, Tolerability, and Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome and Immune Activation Markers in HIV-Infected Participants on Suppressive Antiretroviral Therapy: A Phase II Study
Enrollment Status: Completed
Publish Date: January 06, 2020
Intervention Type: Drug
Study Phase: Phase 2
Dolutegravir Antiretroviral Strategy to Promote Improvement and Reduce Drug Exposure (ASPIRE) Study
Dolutegravir Antiretroviral Strategy to Promote Improvement and Reduce Drug Exposure (ASPIRE) Study
Enrollment Status: Completed
Publish Date: October 14, 2019
Intervention Type: Drug
Study Phase: Phase 3
A Study to Evaluate Dolutegravir Plus Lamivudine Dual Therapy for the Treatment of Naïve HIV-1-infected Participants
A Study to Evaluate Dolutegravir Plus Lamivudine Dual Therapy for the Treatment of Naïve HIV-1-infected Participants
Enrollment Status: Completed
Publish Date: May 09, 2018
Intervention Type: Drug
Study Phase: Phase 2
Sofosbuvir-Containing Regimens Without Interferon For Treatment of Acute HCV in HIV-1 Infected Individuals (SWIFT-C)
Sofosbuvir-Containing Regimens Without Interferon For Treatment of Acute HCV in HIV-1 Infected Individuals (SWIFT-C)
Enrollment Status: Completed
Publish Date: April 27, 2018
Intervention Type: Drug
Study Phase: Phase 1
View 10 Less Clinical Trials

201 Total Publications

Intact and Defective HIV Provirus Changes During Antiretroviral Therapy in People Treated During Acute or Chronic HIV Infection or as HIV Controllers.
Intact and Defective HIV Provirus Changes During Antiretroviral Therapy in People Treated During Acute or Chronic HIV Infection or as HIV Controllers.
Journal: Open forum infectious diseases
Published: August 03, 2025
View All 201 Publications
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75 Francis Street, 
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 (0.1 miles away)
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Daniel R. Kuritzkes, MD received his BS and MS degrees in Molecular Biophysics and Biochemistry from Yale University, and his MD from Harvard Medical School.  He completed his clinical and research training in internal medicine and infectious diseases at Massachusetts General Hospital and was a visiting scientist at the Whitehead Institute for Biomedical Research before joining the faculty at the University of Colorado Health Sciences Center.  Dr. Kuritzkes returned to Harvard Medical School in 2002, where he is now the Harriet Ryan Albee Professor of Medicine and Chief, Division of Infectious Diseases at Brigham and Women’s Hospital.  Dr. Kuritzkes has published extensively on antiretroviral therapy and drug resistance in HIV-1 infection.  He has chaired several multicenter studies of HIV therapy and previously chaired the AIDS Clinical Trials Group.  He has served on numerous NIH committees, including as a member of the NIH Office of AIDS Research Advisory Council.  He is a former member of the Department of Health and Human Services panel on guidelines for antiretroviral therapy and a past Chair of the HIV Medicine Association Board of Directors.  He has been a member of several editorial boards, and serves as an Associate Editor of the Journal of Infectious Diseases.  His research interests focus on HIV therapeutics, antiretroviral drug resistance, HIV eradication and more recently, COVID-19. Dr. Kuritzkes is rated as a Distinguished provider by MediFind in the treatment of HIV/AIDS. His top areas of expertise are HIV/AIDS, Myelitis, AIDS Dementia Complex, and AIDS Dysmorphic Syndrome.

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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

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  • Elite
  • HIV/AIDS
    Dr. Sax is
    Elite
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  • Distinguished
  • Nontuberculous Mycobacterial Lung Disease
    Dr. Sax is
    Distinguished
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  • Advanced
  • AIDS Dementia Complex
    Dr. Sax is
    Advanced
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  • AIDS Dysmorphic Syndrome
    Dr. Sax is
    Advanced
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  • Allergic Bronchopulmonary Aspergillosis
    Dr. Sax is
    Advanced
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  • Myelitis
    Dr. Sax is
    Advanced
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  • Osteomyelitis
    Dr. Sax is
    Advanced
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  • Experienced
  • Babesiosis
    Dr. Sax is
    Experienced
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  • Coccidioidomycosis
    Dr. Sax is
    Experienced
    . Learn about Coccidioidomycosis.
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  • COVID-19
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    Experienced
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  • Cryptococcosis
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  • Endocarditis
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  • Hepatitis
    Dr. Sax is
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View All 21 Experienced Conditions
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