Hope E. Uronis
Experienced in Metastatic Brain Tumor

Dr. Hope E. Uronis

Oncology
Duke Health
Duke Cancer Center
20 Duke Medicine Cir, 
Durham, NC 
On Staff At
Accepting New Patients
Offers Telehealth

Experienced in Metastatic Brain Tumor
Duke Health
Duke Cancer Center
20 Duke Medicine Cir, 
Durham, NC 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

I decided to go to medical school during the early part of college and then never really looked back. I enjoyed every discipline while I was in medical school and had a difficult time selecting a specialty, until I did a rotation in Hematology/Oncology. After observing the relationships that oncologists develop with patients and their families, I knew that medical oncology was the right place for me. Getting to know my patients and their families and helping them achieve their goals, despite a cancer diagnosis, has become extremely important to me. I also enjoy working as part of a multidisciplinary team to make sure that patients get the most comprehensive care possible. When I am not working, I enjoy spending time with family, reading, and running.

Dr. Uronis is rated as an Experienced provider by MediFind in the treatment of Metastatic Brain Tumor. Her top areas of expertise are Gastroesophageal Junction Cancer, Colorectal Cancer, Pancreatic Cancer, Stomach Cancer, and Pancreaticoduodenectomy.

Her clinical research consists of co-authoring 65 peer reviewed articles and participating in 4 clinical trials. MediFind looks at clinical research from the past 15 years.

Specialties
Oncology
Licenses
Internal Medicine in NC
Board Certifications
American Board Of Internal Med, Internal Medicine
American Board Of Internal Med, Medical Oncology
Fellowships
Hematology-Medical Oncology, Duke University Medical Center
Hospital Affiliations
Duke University Hospital
Languages Spoken
English
Gender
Female

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Absolute Total Care South Carolina
  • HMO
  • MANAGED MEDICAID PLAN
  • MEDICARE-MEDICAID PLAN
Aetna
  • EPO
  • HMO
  • POS
  • PPO
Ambetter
  • EPO
  • HMO
  • PPO
Anthem
  • EPO
  • HMO
  • POS
  • PPO
Blue Cross Blue Shield
  • EPO
  • HMO
  • POS
  • PPO
Cambia Health Solutions
  • EPO
  • INSURANCE PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • PPO
Cigna
  • EPO
  • HMO
  • PPO
Health Care Services Corporation
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
  • PPO
Humana
  • HMO
  • INDEMNITY
  • POS
  • PPO
Independent Health
  • EPO
  • POS
  • PPO
Medicaid
  • OTHER MEDICAID
  • STATE MEDICAID
Medicare
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE PART D
Piedmont
  • HMO
  • POS
Premera Blue Cross
  • INSURANCE PLAN
  • MEDICARE MAPD
  • OTHER COMMERCIAL
  • PPO
Sentara Healthcare
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE ASSISTANCE PROGRAM
  • MEDICARE MAPD
  • MEDICARE SNP
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
Spectrum Priority Health
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • OTHER COMMERCIAL
UnitedHealthcare
  • EPO
  • HMO
  • POS
  • PPO
Walgreens
  • MEDICARE DISCOUNT CARD
  • MEDICARE PDP
  • OTHER MEDICARE
Wellcare
  • EPO
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
View 14 Less Insurance Carriers -

Locations

Duke Cancer Center
20 Duke Medicine Cir, Durham, NC 27710
Call: 919-681-6900

Additional Areas of Focus

Dr. Uronis has provided the following conditions as areas of focus. Please note that we may not have enough data to validate their experience in some of these conditions.

Esophageal Cancer
Pancreatic Cancer
Colorectal Cancer
Anal Cancer
Stomach Cancer

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


4 Clinical Trials

A Phase 1b/2, Open Label, Dose Escalation Study of Margetuximab in Combination With Pembrolizumab in Patients With Relapsed/Refractory Advanced HER2+ Gastroesophageal Junction or Gastric Cancer
A Phase 1b/2, Open Label, Dose Escalation Study of Margetuximab in Combination With Pembrolizumab in Patients With Relapsed/Refractory Advanced HER2+ Gastroesophageal Junction or Gastric Cancer
Enrollment Status: Completed
Publish Date: March 17, 2025
Intervention Type: Biological
Study Drug: Margetuximab+Pembrolizumab
Study Phase: Phase 1/Phase 2
A Phase 2 Open-Label Clinical Trial of ADP-A2M4CD8 in Subjects With Advanced Esophageal or Esophagogastric Junction Cancers
A Phase 2 Open-Label Clinical Trial of ADP-A2M4CD8 in Subjects With Advanced Esophageal or Esophagogastric Junction Cancers
Enrollment Status: Terminated
Publish Date: September 04, 2024
Intervention Type: Genetic
Study Phase: Phase 2
Dose Escalation and Expansion Clinical Study to Evaluate the Safety and Efficacy of ELU001 in Subjects Who Have Advanced, Recurrent or Refractory FRα Overexpressing Tumors
Dose Escalation and Expansion Clinical Study to Evaluate the Safety and Efficacy of ELU001 in Subjects Who Have Advanced, Recurrent or Refractory FRα Overexpressing Tumors
Enrollment Status: Terminated
Publish Date: August 07, 2024
Intervention Type: Drug
Study Drug: ELU001
Study Phase: Phase 1/Phase 2
A Single Arm, Phase II Study of Pembrolizumab, Oxaliplatin, and Capecitabine in the First Line Treatment of Patients With Gastro-esophageal Cancer.
A Single Arm, Phase II Study of Pembrolizumab, Oxaliplatin, and Capecitabine in the First Line Treatment of Patients With Gastro-esophageal Cancer.
Enrollment Status: Completed
Publish Date: March 13, 2024
Intervention Type: Drug
Study Drugs: Oxaliplatin, Capecitabine, Pembrolizumab
Study Phase: Phase 2
View 3 Less Clinical Trials

65 Total Publications

Tumor NLRP3 Amplification Promotes Immunotherapy Resistance by Suppressing MHC Class I Expression.
Tumor NLRP3 Amplification Promotes Immunotherapy Resistance by Suppressing MHC Class I Expression.
Journal: medRxiv : the preprint server for health sciences
Published: November 24, 2025
View All 65 Publications
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20 Duke Medicine Cir, 
Durham, NC 
 (0.1 miles away)
919-684-5301
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I am an academic adult and pediatric neuro-oncologist who helps lead The Preston Robert Tisch Brain Tumor Center at Duke. I am the author of more than 500 peer-reviewed articles, reviews, and book chapters, and I have presented extensively at both international and national meetings. I am a committed educator who is a member of the executive and super-executive committees of the Duke University School of Medicine, which are responsible for the recruitment, screening and selection of medical students. I have reviewed grants for the National Institutes of Health for over 15 years, in a spectrum of different study sections. I am the senior editor of CNS Oncology and a reviewer for over 25 academic journals. I serve on the advisory board of a number of organizations, including Voices Against Brain Cancer, the Tug McGraw Foundation, Pinnacle Care, the Pediatric Brain Tumor Foundation, the National Children’s Cancer Society, and the American Brain Tumor Association. Dr. Friedman is rated as an Elite provider by MediFind in the treatment of Metastatic Brain Tumor. His top areas of expertise are Glioma, Astrocytoma, Glioblastoma, and Brain Tumor.

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Distinguished in Metastatic Brain Tumor
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Duke Cancer Center

20 Duke Medicine Cir, 
Durham, NC 
 (0.1 miles away)
919-681-6900
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Accepting New Patients
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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

Find Dr. Uronis's expertise for a condition
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  • Elite
  • Gastroesophageal Junction Cancer
    Dr. Uronis is
    Elite
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  • Distinguished
  • Anal Cancer
    Dr. Uronis is
    Distinguished
    . Learn about Anal Cancer.
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  • Cholangiocarcinoma (Bile Duct Cancer)
    Dr. Uronis is
    Distinguished
    . Learn about Cholangiocarcinoma (Bile Duct Cancer).
    See more Cholangiocarcinoma (Bile Duct Cancer) experts
  • Colorectal Cancer
    Dr. Uronis is
    Distinguished
    . Learn about Colorectal Cancer.
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  • Familial Colorectal Cancer
    Dr. Uronis is
    Distinguished
    . Learn about Familial Colorectal Cancer.
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  • Familial Pancreatic Cancer
    Dr. Uronis is
    Distinguished
    . Learn about Familial Pancreatic Cancer.
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  • Lynch Syndrome
    Dr. Uronis is
    Distinguished
    . Learn about Lynch Syndrome.
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View All 9 Distinguished Conditions
  • Advanced
  • Adult Soft Tissue Sarcoma
    Dr. Uronis is
    Advanced
    . Learn about Adult Soft Tissue Sarcoma.
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  • Ampullary Cancer
    Dr. Uronis is
    Advanced
    . Learn about Ampullary Cancer.
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  • Clear Cell Sarcoma
    Dr. Uronis is
    Advanced
    . Learn about Clear Cell Sarcoma.
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  • Familial Prostate Cancer
    Dr. Uronis is
    Advanced
    . Learn about Familial Prostate Cancer.
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  • Mesothelioma
    Dr. Uronis is
    Advanced
    . Learn about Mesothelioma.
    See more Mesothelioma experts
  • Pancreatoblastoma
    Dr. Uronis is
    Advanced
    . Learn about Pancreatoblastoma.
    See more Pancreatoblastoma experts
View All 7 Advanced Conditions
  • Experienced
  • ALK-Positive Non-Small Cell Lung Cancer
    Dr. Uronis is
    Experienced
    . Learn about ALK-Positive Non-Small Cell Lung Cancer.
    See more ALK-Positive Non-Small Cell Lung Cancer experts
  • Appendix Cancer
    Dr. Uronis is
    Experienced
    . Learn about Appendix Cancer.
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  • EGFR Positive Lung Cancer
    Dr. Uronis is
    Experienced
    . Learn about EGFR Positive Lung Cancer.
    See more EGFR Positive Lung Cancer experts
  • Esophageal Cancer
    Dr. Uronis is
    Experienced
    . Learn about Esophageal Cancer.
    See more Esophageal Cancer experts
  • Fibrolamellar Carcinoma
    Dr. Uronis is
    Experienced
    . Learn about Fibrolamellar Carcinoma.
    See more Fibrolamellar Carcinoma experts
  • Gallbladder Adenocarcinoma
    Dr. Uronis is
    Experienced
    . Learn about Gallbladder Adenocarcinoma.
    See more Gallbladder Adenocarcinoma experts
View All 23 Experienced Conditions
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