Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Primary objectives: Primary objectives are to assess and define benchmarks of the surgical outcome in the form of extent of resection, functionality, and quality of life after resection of juxta medullary tumors Secondary objectives: Assessment of variables leading to better outcome through regression analysis: 1. Influence of surgical approach on functionality, pain, and quality of life 2. Comparison between patient with severe neurological (McCormick scale 3-5) to patients with mild deficits (McCormick scale 1-2) 3. Role of intraoperative monitoring (IOM) in extent of resection and neurological deficits Assessment of treatment variations: 1. Assessment of risk factors for incomplete resection 2. Non inferiority of unilateral approach to achieve gross total resection of spinal meningioma, schwannoma and cauda ependymoma 3. Role of bed rest after surgery to prevent cerebro-spinal fluid leakage 4. Influence of laminectomy on cerebro-spinal fluid leakage Quality indicators: assessments of length of hospital stay, 30- and 90-days re-admissions, 30- and 90-days re-surgery, nosocomial infections

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult, age ≥18 years, patients treated on intraspinal, extra medullary tumor

• Patients must have sufficient cognitive and language skills to give informed consent

Locations
Other Locations
Germany
University Hospital Muenster
RECRUITING
Münster
Contact Information
Primary
Michael Schwake, MD
schwakem@uni-muenster.de
+49 251 8343930
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2027-12
Participants
Target number of participants: 100
Sponsors
Collaborators: Universitätsklinikum Hamburg-Eppendorf, Medical University of Cologne, Technical University of Munich, University Hospital Freiburg
Leads: University Hospital Muenster

This content was sourced from clinicaltrials.gov

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