PRediction of DIverse Glucocorticoids ToxIcity OUtcomeS

Status: Recruiting
Location: See all (11) locations...
Study Type: Observational
SUMMARY

To date, there is no available tool that allows, at individual level, determination of the probability to develop clinically relevant complications of prolonged glucocorticoid therapy. In patients with inflammatory rheumatic disorders requiring prolonged glucocorticoid therapy, such tool could be useful to adapt first-line treatment decisions (in daily practice and in future clinical trials). The main objective of the study is to identify routine clinical, biological and DXA baseline characteristics predictive of the occurrence of clinically relevant complications of glucocorticoid therapy at 1 year, in order to propose a predictive score.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Life expectancy \> 1 year.

• Indication to initiate prolonged glucocorticoid therapy at a dosage ≥ 15 mg/day for the treatment of an inflammatory rheumatic disease.

• Initial treatment or relapse.

• Previsional treatment duration \> 3 months.

Locations
Other Locations
France
CHU d'Angers
RECRUITING
Angers
CHRU de Brest
RECRUITING
Brest
CHD Vendée
RECRUITING
La Roche-sur-yon
CH Le Mans
RECRUITING
Le Mans
CH des Pays de Morlaix
RECRUITING
Morlaix
CHU de Nantes
RECRUITING
Nantes
CHR d'Orléans
NOT_YET_RECRUITING
Orléans
<CHU de Poitiers
RECRUITING
Poitiers
CHIC Quimper
RECRUITING
Quimper
Clinique St Exupéry
RECRUITING
Toulouse
CHU de Tours
RECRUITING
Tours
Contact Information
Primary
Dewi GUELLEC
dewi.guellec@chu-brest.fr
02-98-34-72-64
Time Frame
Start Date: 2021-03-18
Estimated Completion Date: 2026-03-18
Participants
Target number of participants: 300
Sponsors
Leads: University Hospital, Brest

This content was sourced from clinicaltrials.gov