Dr. Yuka Manabe

Dr. Yukari Manabe is a Professor in the Division of Infectious Diseases in the Department of Medicine with secondary appointments in the Bloomberg School of Public Health Department of International Health and the Department of Microbiology and Molecular Immunology. Dr. Manabe began her career working on the basic science aspects of tuberculosis (TB) immunopathogenesis in comparative animal models of infection, particularly latency, reactivation, and immune reconstitution inflammatory syndrome (IRIS) in the rabbit model within the Johns Hopkins Center for Tuberculosis Research. In 2007, she was seconded to the Infectious Diseases Institute (IDI) at Makerere College of Health Sciences as the Associate Medical Laboratory Director of the College of American Pathologists certified Makerere University-Johns Hopkins University Clinical Core Lab to study antiretroviral associated TB and IRIS. She then became the Head of Research at the IDI in 2008 until 2012 where she built research capacity and infrastructure to train Ugandan investigators. Since returning to Hopkins, she has become the PI of the Johns Hopkins POC STD Center (U54 funded through NIH) which is part of the newly formed Johns Hopkins Center for Innovative Diagnostics for Infectious Diseases. The Center develops new diagnostics, funds development for point-of-care diagnostics, evaluates (validation and verification) new technology, and performs pre-clinical studies to accelerate the development of infectious disease assays (STIs, TB, acute febrile illness, HIV, syphilis, viral hepatitis). Dr. Manabe is particularly interested in rapid, point-of-care infectious disease diagnostics suitable for the resource-limited settings particularly in sub-Saharan Africa (SSA). Her research has focused on accuracy testing of various rapid, point-of-care diagnostics for HIV and related infectious diseases of clinical importance in SSA. Studies have ranged from evaluations of performance accuracy through clinical implementation science studies on the patient-centered outcomes and impactful use of new rapid diagnostics. Dr. Manabe obtained her undergraduate degree from Yale University and her M.D. from Columbia University College of Physicians and Surgeons. After completing both her residency in Internal Medicine and fellowship in Infectious Diseases at Johns Hopkins Hospital, she joined the faculty in 1999.

Dr. Manabe is rated as a Distinguished provider by MediFind in the treatment of Syphilis. Her top areas of expertise are HIV/AIDS, Cryptococcosis, Gonorrhea, Meningitis, and Tissue Biopsy.

Her clinical research consists of co-authoring 318 peer reviewed articles and participating in 4 clinical trials. MediFind looks at clinical research from the past 15 years. In particular, she has co-authored 19 articles in the study of Syphilis.