Dr. Chetan Malpe

The maturation of GABAA receptor-mediated signaling from depolarizing to inhibitory is an age-related process controlled by cation chloride cotransporters, such as KCC2. As a result, GABA exerts dual functions, being an important neurotrophic factor during early development and the principal inhibitory neurotransmitter of the mature central nervous system. In our laboratory we have been investigating the age and mechanisms through which early life stressors and seizures may disrupt the normal patterns of brain development, by disrupting the neurotrophic effects of GABA. We are also studying methods to reverse these adverse processes. Furthermore, we are very interested in understanding how epileptogenesis proceeds in the developing brain and what is the specific role of GABAA receptors in this process. Dr. Galanopoulou is rated as an Elite provider by MediFind in the treatment of West Syndrome. Her top areas of expertise are West Syndrome, Spasmus Nutans, Post-Traumatic Epilepsy, and Epilepsy.

Orrin Devinsky is a Neurologist and a General Surgeon in New York, New York. Dr. Devinsky is rated as an Elite provider by MediFind in the treatment of West Syndrome. His top areas of expertise are Myoclonic Epilepsy, Dravet Syndrome, Seizures, Epilepsy, and Deep Brain Stimulation.

Vandana Soni is a Neurologist in Plainview, New York. Dr. Soni is rated as a Distinguished provider by MediFind in the treatment of West Syndrome. Her top areas of expertise are West Syndrome, Myoclonic Epilepsy, Epilepsy with Myoclonic-Atonic Seizures, and Infant Epilepsy with Migrant Focal Crisis.