Danielle N. Margalit
Advanced in Melanoma

Dr. Danielle N. Margalit

Radiation Oncology
Brigham and Women’s Hospital
Brigham And Women's Hospital, Department Of Radiation Oncology
75 Francis Street, 
Boston, MA 

Advanced in Melanoma
Brigham and Women’s Hospital
Brigham And Women's Hospital, Department Of Radiation Oncology
75 Francis Street, 
Boston, MA 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

"Dr. Margalit is an Associate Professor of Radiation Oncology at Harvard Medical School and a member of the Head and Neck Oncology Program and the Center for Cutaneous Oncology, specializing in the treatment of tumors of the head and neck, and skin. Dr. Margalit received her medical degree from Harvard Medical School and completed her residency in radiation oncology at the Harvard Radiation Oncology Program. She completed a post-doctoral fellowship in Cancer Epidemiology and Master of Public Health in Clinical Epidemiology at the Harvard School of Public Health.Dr. Margalit teaches and mentors students from Harvard Medical School and Residents of the Harvard Radiation Oncology Program. She is an active participant on national committees of the American Society for Radiation Oncology (ASTRO), American Board of Radiology (ABR), and American Society for Clinical Oncology (ASCO).  She is a senior editor for the International Journal of Radiation Oncology ● Biology ● Physics and serves as the Chair of the multi-disciplinary American Radium Society Appropriate Use Criteria Committee for Head and Neck Cancer. Dr. Margalit’s research focuses on integrating new technologies and targeted therapies to improve cure rates while minimizing side effects of cancer treatment.She is the recipient of multiple awards including the inaugural Brigham and Women's Hospital/Dana-Farber Department of Radiation Oncology Outstanding Clinician Award that recognizes ""expert patient care, demonstrates compassion and respect, and pursues excellence with integrity.""".

Dr. Margalit is rated as an Advanced provider by MediFind in the treatment of Melanoma. Her top areas of expertise are Merkel Cell Carcinoma, Adenoid Cystic Carcinoma, Head and Neck Squamous Cell Carcinoma (HNSCC), and Melanoma.

Her clinical research consists of co-authoring 86 peer reviewed articles and participating in 3 clinical trials. MediFind looks at clinical research from the past 15 years.

Graduate Institution
Harvard Medical School, 2006
Residency
Brigham and Women's Hospital, 2007 - 2011
Specialties
Radiation Oncology
Licenses
Internal Medicine in MA
Board Certifications
Radiation Oncology
Hospital Affiliations
Brigham And Women's Hospital
Languages Spoken
English
Gender
Female

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
Anthem
  • EPO
  • HMO
  • POS
  • PPO
Blue Cross Blue Shield
  • EPO
  • HMO
  • POS
  • PPO
BMC HealthNet
  • HMO
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE SNP
Cigna
  • EPO
  • HMO
  • PPO
Commonwealth Care Alliance
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
Health New England
  • HMO
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • OTHER COMMERCIAL
Managed Medicaid
  • OTHER MANAGED MEDICAID
Mass General Brigham Health Plan
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • PPO
Medicaid
  • OTHER MEDICAID
  • STATE MEDICAID
Tufts
  • HMO
UnitedHealthcare
  • EPO
  • HMO
  • POS
  • PPO
Wellcare
  • EPO
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
View 8 Less Insurance Carriers -

Locations

Brigham and Women's Hospital, Department of Radiation Oncology
75 Francis Street, Boston, MA 02115
Call: 617-632-5296
Other Locations
Dana-Farber Brigham Cancer Center
450 Brookline Avenue, Boston, MA 02115
Call: 617-632-5296
Dana-Farber Cancer Institute, Center for Cutaneous Oncology
450 Brookline Avenue, Boston, MA 02115
Call: 617-632-5296
Dana-Farber Cancer Institute, Head and Neck Cancer Treatment Center
450 Brookline Avenue, Boston, MA 02115
Call: 617-632-5296

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


3 Clinical Trials

Immunotherapy With MK-3475 in Locoregionally Advanced, Surgically Resectable Head and Neck Squamous Cell Carcinoma
Immunotherapy With MK-3475 in Locoregionally Advanced, Surgically Resectable Head and Neck Squamous Cell Carcinoma
Enrollment Status: Completed
Publish Date: January 15, 2026
Intervention Type: Radiation, Procedure, Biological, Drug
Study Drugs: Pembrolizumab, Cisplatin
Study Phase: Phase 2
A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients With Early-Stage, P16-Positive, Non-Smoking Associated Oropharyngeal Cancer
A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients With Early-Stage, P16-Positive, Non-Smoking Associated Oropharyngeal Cancer
Enrollment Status: Active_not_recruiting
Publish Date: October 31, 2025
Intervention Type: Other, Procedure, Drug, Biological, Radiation
Study Drugs: Cisplatin, Nivolumab
Study Phase: Phase 2/Phase 3
Phase I Study of Afatinib With Postoperative Radiation Therapy for Intermediate and High Risk Squamous Cancer of the Head and Neck (SCCHN)
Phase I Study of Afatinib With Postoperative Radiation Therapy for Intermediate and High Risk Squamous Cancer of the Head and Neck (SCCHN)
Enrollment Status: Completed
Publish Date: May 01, 2025
Intervention Type: Drug, Radiation
Study Phase: Phase 1
View 2 Less Clinical Trials

86 Total Publications

Executive Summary of the American Radium Society Appropriate Use Criteria for Management of Early Glottic Cancer: A Review.
Executive Summary of the American Radium Society Appropriate Use Criteria for Management of Early Glottic Cancer: A Review.
Journal: JAMA otolaryngology-- head & neck surgery
Published: August 28, 2025
View All 86 Publications
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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

Find Dr. Margalit's expertise for a condition
ConditionClose
    • Distinguished
    • Adenoid Cystic Carcinoma
      Dr. Margalit is
      Distinguished
      . Learn about Adenoid Cystic Carcinoma.
      See more Adenoid Cystic Carcinoma experts
    • Head and Neck Squamous Cell Carcinoma (HNSCC)
      Dr. Margalit is
      Distinguished
      . Learn about Head and Neck Squamous Cell Carcinoma (HNSCC).
      See more Head and Neck Squamous Cell Carcinoma (HNSCC) experts
    • Merkel Cell Carcinoma
      Dr. Margalit is
      Distinguished
      . Learn about Merkel Cell Carcinoma.
      See more Merkel Cell Carcinoma experts
    • Advanced
    • Acinic Cell Carcinoma of Salivary Glands
      Dr. Margalit is
      Advanced
      . Learn about Acinic Cell Carcinoma of Salivary Glands.
      See more Acinic Cell Carcinoma of Salivary Glands experts
    • Adult Soft Tissue Sarcoma
      Dr. Margalit is
      Advanced
      . Learn about Adult Soft Tissue Sarcoma.
      See more Adult Soft Tissue Sarcoma experts
    • Alveolar Soft Part Sarcoma
      Dr. Margalit is
      Advanced
      . Learn about Alveolar Soft Part Sarcoma.
      See more Alveolar Soft Part Sarcoma experts
    • Eccrine Porocarcinoma
      Dr. Margalit is
      Advanced
      . Learn about Eccrine Porocarcinoma.
      See more Eccrine Porocarcinoma experts
    • Epithelial-Myoepithelial Carcinoma
      Dr. Margalit is
      Advanced
      . Learn about Epithelial-Myoepithelial Carcinoma.
      See more Epithelial-Myoepithelial Carcinoma experts
    • Ganglioneuroblastoma
      Dr. Margalit is
      Advanced
      . Learn about Ganglioneuroblastoma.
      See more Ganglioneuroblastoma experts
    View All 23 Advanced Conditions
    • Experienced
    • Anaplastic Thyroid Cancer
      Dr. Margalit is
      Experienced
      . Learn about Anaplastic Thyroid Cancer.
      See more Anaplastic Thyroid Cancer experts
    • Bone Tumor
      Dr. Margalit is
      Experienced
      . Learn about Bone Tumor.
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    • Epithelioid Sarcoma
      Dr. Margalit is
      Experienced
      . Learn about Epithelioid Sarcoma.
      See more Epithelioid Sarcoma experts
    • Ewing Sarcoma
      Dr. Margalit is
      Experienced
      . Learn about Ewing Sarcoma.
      See more Ewing Sarcoma experts
    • Fibrosarcoma
      Dr. Margalit is
      Experienced
      . Learn about Fibrosarcoma.
      See more Fibrosarcoma experts
    • Follicular Thyroid Cancer
      Dr. Margalit is
      Experienced
      . Learn about Follicular Thyroid Cancer.
      See more Follicular Thyroid Cancer experts
    View All 18 Experienced Conditions
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