Neurosurgical Outcome Network Per La Predizione Dell'outcome in Neurochirurgia

Status: Recruiting
Location: See all (27) locations...
Study Type: Observational
SUMMARY

The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared. This study aims to assess outcomes and their predictors using measures agreed upon by the participating centers. Standardizing the evaluation of outcomes and predictors improves the quality of research, allows for data comparison, and facilitates a common language in routine clinical practice. Most importantly, it influences therapeutic decisions in various neurosurgical conditions. Clinically, the identified predictors can also be used during preoperative assessments to provide more precise guidance to patients undergoing surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Neuro-oncological pathology: supratentorial and subtentorial tumors, intra and extra axial tumors excluding the skull base (anterior, middle and posterior fossa; sellar and parasellar region)

• Basicranial pathology: tumors originating from the anterior cranial fossa, middle cranial fossa and posterior cranial fossa, sellar region with or without supratentorial/parasellar development.

• Vascular pathology: aneurysms, AVMs, cavernomas, other pathologies (Moyamoya disease, dural fistulas, nontraumatic hematomas)

• Traumatic pathology: diffuse damage (nonvisible diffuse damage, diffuse damage, diffuse damage with edema, diffuse damage with shift) and focal damage (acute/subacute/chronic subdural hematoma, extradural hematoma, subarachnoid hemorrhage, intraparenchymal hematoma, fractures); hydrocephalus. The inclusion criterion for chronic subdural hematoma is recent bleeding for TBI with CT finding of chronic subdural hematoma candidate for evacuation surgery.

• Spinal pathology: degenerative cervical (anterior/posterior), myelopathic, and trauma pathology; instrumented, uninstrumented thoracolumbar pathology (disc pathology, canal pathology), and trauma pathology; oncologic spinal pathology.

• Functional pathology: Parkinson's disease, spasticity, trigeminal neuralgia, craniofacial pain/algia, neuropathic pain, tremor, dystonias, obsessive compulsive disorder, drug-resistant epilepsies, depression. Normotensive hydrocephalus.

• Peripheral nervous system pathology: peripheral nerve compression syndromes, peripheral nerve and plexus tumors, brachial plexus and peripheral nerve trauma (contusion and section)

• Malformative pathology: Chiari malformation type 1 and craniostenoses including both those framed in malformative syndromes and those not framed in malformative syndromes (monosutural craniostenoses: trigonocephaly, plagiocephaly, scaphocephaly; multisutural craniostenoses). Malformative hydrocephalus.

• For cognitive and psychological assessment: age 18 years or older; adequate understanding of Italian language; diagnosis of glioma, meningioma, vascular pathology, spinal pathology

Locations
Other Locations
Italy
1. ASST Papa Giovanni XXIII
ACTIVE_NOT_RECRUITING
Bergamo
Fondazione Poliambulanza Istituto Ospedaliero
ACTIVE_NOT_RECRUITING
Brescia
Spedali Civili Brescia
ACTIVE_NOT_RECRUITING
Brescia
Azienda Ospedaliero Universitaria Policlinico G. Rodolico - San Marco
RECRUITING
Catania
ASST Lariana, Ospedale S. Anna
ACTIVE_NOT_RECRUITING
Como
ASST Cremona
ACTIVE_NOT_RECRUITING
Cremona
Azienda Ospedaliero Universitaria Careggi
RECRUITING
Florence
Ospedale F. Spaziani di Frosinone
RECRUITING
Frosinone
Ospedale Moriggia Pelascini
ACTIVE_NOT_RECRUITING
Gravedona
Ospedale Alessandro Manzoni
ACTIVE_NOT_RECRUITING
Lecco
ASST Ovest Milanese
ACTIVE_NOT_RECRUITING
Legnano
Ospedali Riuniti di Livorno -Azienda USL Toscana nord ovest
RECRUITING
Livorno
ASST Fatebenefratelli Sacco
ACTIVE_NOT_RECRUITING
Milan
ASST Santi Paolo e Carlo
RECRUITING
Milan
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
ACTIVE_NOT_RECRUITING
Milan
Fondazione IRCCS Istituto Neurologico Carlo Besta
RECRUITING
Milan
Istituto Clinico Città Studi
ACTIVE_NOT_RECRUITING
Milan
Fondazione IRCCS San Gerardo dei Tintori
ACTIVE_NOT_RECRUITING
Monza
Policlinico di Monza
RECRUITING
Monza
A.R.N.A.S. Ospedali Civico di Palermo
RECRUITING
Palermo
Azienda Ospedaliero Universitaria di Parma
ACTIVE_NOT_RECRUITING
Parma
Fondazione IRCCS Policlinico San Matteo
ACTIVE_NOT_RECRUITING
Pavia
ASL Roma 1
RECRUITING
Roma
Fondazione Policlinico Universitario Gemelli di Roma
RECRUITING
Roma
IRCCS Istituto Clinico Humanitas
ACTIVE_NOT_RECRUITING
Rozzano
ASST della Valtellina ed Alto Lario
ACTIVE_NOT_RECRUITING
Sondrio
Azienda Sanitaria Universitaria Friuli Centrale di Udine
RECRUITING
Udine
Contact Information
Primary
Paolo Ferroli, MD
paolo.ferroli@istituto-besta.it
+39 02 2394 2411
Backup
Morgan A Broggi, MD
morgan.broggi@istituto-besta.it
+39 02 2394 2411
Time Frame
Start Date: 2022-12-05
Estimated Completion Date: 2027-06
Participants
Target number of participants: 4500
Sponsors
Leads: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

This content was sourced from clinicaltrials.gov