Advanced in Pol 3-Related Leukodystrophy

Dr. Katherine D. Mathews

Neurology | Pediatrics | Pediatric Neurology
University of Iowa Health Care
State University Of Iowa
200 Hawkins Dr, 
Iowa City, IA 
Accepting New Patients

Advanced in Pol 3-Related Leukodystrophy
University of Iowa Health Care
State University Of Iowa
200 Hawkins Dr, 
Iowa City, IA 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

Katherine Mathews is a Neurologist and a Pediatrics provider in Iowa City, Iowa. Dr. Mathews is rated as an Advanced provider by MediFind in the treatment of Pol 3-Related Leukodystrophy. Her top areas of expertise are Limb-Girdle Muscular Dystrophy Type 2I, Limb-Girdle Muscular Dystrophy, Dystrophinopathy, and Friedreich Ataxia. Dr. Mathews is currently accepting new patients.

Her clinical research consists of co-authoring 125 peer reviewed articles and participating in 16 clinical trials. MediFind looks at clinical research from the past 15 years.

Specialties
Neurology
Pediatrics
Pediatric Neurology
Licenses
Psychiatry & Neurology in IA
Hospital Affiliations
University Of Iowa Hospital & Clinics
Languages Spoken
English
Gender
Female

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Aetna
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Wellcare
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Wellmark
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Locations

STATE UNIVERSITY OF IOWA
200 Hawkins Dr, Iowa City, IA 52242
Call: 319-356-1616

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


16 Clinical Trials

A Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Tideglusib Versus Placebo for the Treatment of Children and Adolescents With Congenital Myotonic Dystrophy (REACH CDM)
A Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Tideglusib Versus Placebo for the Treatment of Children and Adolescents With Congenital Myotonic Dystrophy (REACH CDM)
Enrollment Status: Completed
Publish Date: October 08, 2025
Intervention Type: Drug
Study Drug: Tideglusib
Study Phase: Phase 2/Phase 3
A Phase 2 Study of the Safety, Efficacy, and Pharmacodynamics of RTA 408 in the Treatment of Friedreich's Ataxia (MOXIe)
A Phase 2 Study of the Safety, Efficacy, and Pharmacodynamics of RTA 408 in the Treatment of Friedreich's Ataxia (MOXIe)
Enrollment Status: Active_not_recruiting
Publish Date: October 07, 2025
Intervention Type: Drug
Study Drug: Omaveloxolone
Study Phase: Phase 2
A Double-Blind, Placebo-Controlled, Multi-Center Study With an Open-Label Extension to Evaluate the Efficacy and Safety of SRP-4045 and SRP-4053 in Patients With Duchenne Muscular Dystrophy
A Double-Blind, Placebo-Controlled, Multi-Center Study With an Open-Label Extension to Evaluate the Efficacy and Safety of SRP-4045 and SRP-4053 in Patients With Duchenne Muscular Dystrophy
Enrollment Status: Active_not_recruiting
Publish Date: September 23, 2025
Intervention Type: Drug
Study Drugs: SRP-4045 Exon 45-Skipping Treatment, SRP-4053 Exon 53-Skipping Treatment
Study Phase: Phase 3
A Phase 3 Multinational, Randomized, Double-Blind, Placebo-Controlled Systemic Gene Delivery Study to Evaluate the Safety and Efficacy of SRP-9001 in Subjects With Duchenne Muscular Dystrophy (EMBARK)
A Phase 3 Multinational, Randomized, Double-Blind, Placebo-Controlled Systemic Gene Delivery Study to Evaluate the Safety and Efficacy of SRP-9001 in Subjects With Duchenne Muscular Dystrophy (EMBARK)
Enrollment Status: Completed
Publish Date: July 08, 2025
Intervention Type: Genetic
Study Phase: Phase 3
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety and Efficacy of Intravenous Delivery of Allogeneic Cardiosphere-Derived Cells in Subjects With Duchenne Muscular Dystrophy
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety and Efficacy of Intravenous Delivery of Allogeneic Cardiosphere-Derived Cells in Subjects With Duchenne Muscular Dystrophy
Enrollment Status: Completed
Publish Date: May 28, 2025
Intervention Type: Drug, Biological
Study Phase: Phase 2
Open Label, Long-term Safety, Tolerability, and Efficacy Study of GIVINOSTAT in All DMD Patients Who Have Been Previously Treated in One of the GIVINOSTAT Studies
Open Label, Long-term Safety, Tolerability, and Efficacy Study of GIVINOSTAT in All DMD Patients Who Have Been Previously Treated in One of the GIVINOSTAT Studies
Enrollment Status: Active_not_recruiting
Publish Date: April 30, 2025
Intervention Type: Drug
Study Phase: Phase 2/Phase 3
A Phase 2, Two-Part, Multiple-Ascending-Dose Study of SRP-5051 for Dose Determination, Then Dose Expansion, in Patients With Duchenne Muscular Dystrophy Amenable to Exon 51-Skipping Treatment
A Phase 2, Two-Part, Multiple-Ascending-Dose Study of SRP-5051 for Dose Determination, Then Dose Expansion, in Patients With Duchenne Muscular Dystrophy Amenable to Exon 51-Skipping Treatment
Enrollment Status: Terminated
Publish Date: March 10, 2025
Intervention Type: Drug
Study Drug: SRP-5051 Exon 51-Skipping Treatment
Study Phase: Phase 2
Clinical Outcome Measures in Friedreich's Ataxia
Clinical Outcome Measures in Friedreich's Ataxia
Enrollment Status: Active_not_recruiting
Publish Date: October 04, 2024
Trial of Pamrevlumab (FG-3019), a Monoclonal Antibody to Connective Tissue Growth Factor, in Non-Ambulatory Subjects With Duchenne Muscular Dystrophy
Trial of Pamrevlumab (FG-3019), a Monoclonal Antibody to Connective Tissue Growth Factor, in Non-Ambulatory Subjects With Duchenne Muscular Dystrophy
Enrollment Status: Terminated
Publish Date: August 27, 2024
Intervention Type: Drug
Study Drug: Pamrevlumab
Study Phase: Phase 2
A Phase 3, Randomized, Double-Blind, Trial of Pamrevlumab (FG-3019) or Placebo in Combination With Systemic Corticosteroids in Ambulatory Subjects With Duchenne Muscular Dystrophy (DMD)
A Phase 3, Randomized, Double-Blind, Trial of Pamrevlumab (FG-3019) or Placebo in Combination With Systemic Corticosteroids in Ambulatory Subjects With Duchenne Muscular Dystrophy (DMD)
Enrollment Status: Terminated
Publish Date: August 26, 2024
Intervention Type: Drug
Study Drug: Pamrevlumab
Study Phase: Phase 3
A Phase 3, Randomized, Double-Blind Trial of Pamrevlumab (FG-3019) or Placebo in Combination With Systemic Corticosteroids in Subjects With Non-ambulatory Duchenne Muscular Dystrophy (DMD)
A Phase 3, Randomized, Double-Blind Trial of Pamrevlumab (FG-3019) or Placebo in Combination With Systemic Corticosteroids in Subjects With Non-ambulatory Duchenne Muscular Dystrophy (DMD)
Enrollment Status: Terminated
Publish Date: March 12, 2024
Intervention Type: Drug
Study Drug: Pamrevlumab
Study Phase: Phase 3
Randomised, Double Blind, Placebo Controlled, Multicentre Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Duchenne Muscular Dystrophy
Randomised, Double Blind, Placebo Controlled, Multicentre Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Duchenne Muscular Dystrophy
Enrollment Status: Completed
Publish Date: February 02, 2023
Intervention Type: Drug
Study Drug: Givinostat
Study Phase: Phase 3
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy
Enrollment Status: Terminated
Publish Date: September 26, 2022
Intervention Type: Drug
Study Phase: Phase 2
A Multicenter Open-Label Study on the Safety and Efficacy of Deflazacort (Emflaza) in Subjects With Limb-Girdle Muscular Dystrophy 2I (LGMD2I)
A Multicenter Open-Label Study on the Safety and Efficacy of Deflazacort (Emflaza) in Subjects With Limb-Girdle Muscular Dystrophy 2I (LGMD2I)
Enrollment Status: Terminated
Publish Date: June 27, 2022
Intervention Type: Drug
Study Phase: Phase 3
An Open-Label, Multi-Center, Study With a Concurrent Untreated Control Arm to Evaluate the Efficacy and Safety of Eteplirsen in Duchenne Muscular Dystrophy
An Open-Label, Multi-Center, Study With a Concurrent Untreated Control Arm to Evaluate the Efficacy and Safety of Eteplirsen in Duchenne Muscular Dystrophy
Enrollment Status: Completed
Publish Date: January 25, 2021
Intervention Type: Drug
Study Phase: Phase 3
An Open-Label, Multi-Center Study to Evaluate the Safety, Efficacy and Tolerability of Eteplirsen in Early Stage Duchenne Muscular Dystrophy
An Open-Label, Multi-Center Study to Evaluate the Safety, Efficacy and Tolerability of Eteplirsen in Early Stage Duchenne Muscular Dystrophy
Enrollment Status: Completed
Publish Date: January 25, 2021
Intervention Type: Drug
Study Phase: Phase 2
View 15 Less Clinical Trials

125 Total Publications

279th ENMC international workshop: Classification, clinical care, outcome measures and biomarkers in childhood onset facioscapulohumeral dystrophy: towards standardizing clinical care and ensuring clinical trial readiness. Hoofddorp, The Netherlands, 1-3 November 2024.
279th ENMC international workshop: Classification, clinical care, outcome measures and biomarkers in childhood onset facioscapulohumeral dystrophy: towards standardizing clinical care and ensuring clinical trial readiness. Hoofddorp, The Netherlands, 1-3 November 2024.
Journal: Neuromuscular disorders : NMD
Published: September 26, 2025
View All 125 Publications
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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

Find Dr. Mathews's expertise for a condition
ConditionClose
  • Elite
  • Becker Muscular Dystrophy
    Dr. Mathews is
    Elite
    . Learn about Becker Muscular Dystrophy.
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  • Duchenne Muscular Dystrophy
    Dr. Mathews is
    Elite
    . Learn about Duchenne Muscular Dystrophy.
    See more Duchenne Muscular Dystrophy experts
  • Dystrophinopathy
    Dr. Mathews is
    Elite
    . Learn about Dystrophinopathy.
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  • Friedreich Ataxia
    Dr. Mathews is
    Elite
    . Learn about Friedreich Ataxia.
    See more Friedreich Ataxia experts
  • Fukuyama Type Muscular Dystrophy
    Dr. Mathews is
    Elite
    . Learn about Fukuyama Type Muscular Dystrophy.
    See more Fukuyama Type Muscular Dystrophy experts
  • Limb-Girdle Muscular Dystrophy
    Dr. Mathews is
    Elite
    . Learn about Limb-Girdle Muscular Dystrophy.
    See more Limb-Girdle Muscular Dystrophy experts
View All 9 Elite Conditions
  • Distinguished
  • Delta-Sarcoglycanopathy
    Dr. Mathews is
    Distinguished
    . Learn about Delta-Sarcoglycanopathy.
    See more Delta-Sarcoglycanopathy experts
  • Distal Myopathy 2
    Dr. Mathews is
    Distinguished
    . Learn about Distal Myopathy 2.
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  • Drug Induced Dyskinesia
    Dr. Mathews is
    Distinguished
    . Learn about Drug Induced Dyskinesia.
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  • Dysferlinopathy
    Dr. Mathews is
    Distinguished
    . Learn about Dysferlinopathy.
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  • Emery-Dreifuss Muscular Dystrophy
    Dr. Mathews is
    Distinguished
    . Learn about Emery-Dreifuss Muscular Dystrophy.
    See more Emery-Dreifuss Muscular Dystrophy experts
  • Facioscapulohumeral Muscular Dystrophy (FSHD)
    Dr. Mathews is
    Distinguished
    . Learn about Facioscapulohumeral Muscular Dystrophy (FSHD).
    See more Facioscapulohumeral Muscular Dystrophy (FSHD) experts
View All 16 Distinguished Conditions
  • Advanced
  • Acute Cerebellar Ataxia
    Dr. Mathews is
    Advanced
    . Learn about Acute Cerebellar Ataxia.
    See more Acute Cerebellar Ataxia experts
  • Behr Syndrome
    Dr. Mathews is
    Advanced
    . Learn about Behr Syndrome.
    See more Behr Syndrome experts
  • Congenital Muscular Dystrophy Type 1A
    Dr. Mathews is
    Advanced
    . Learn about Congenital Muscular Dystrophy Type 1A.
    See more Congenital Muscular Dystrophy Type 1A experts
  • Cortical Dysplasia
    Dr. Mathews is
    Advanced
    . Learn about Cortical Dysplasia.
    See more Cortical Dysplasia experts
  • Cramp-Fasciculation Syndrome
    Dr. Mathews is
    Advanced
    . Learn about Cramp-Fasciculation Syndrome.
    See more Cramp-Fasciculation Syndrome experts
  • Early Infantile Epileptic Encephalopathy
    Dr. Mathews is
    Advanced
    . Learn about Early Infantile Epileptic Encephalopathy.
    See more Early Infantile Epileptic Encephalopathy experts
View All 25 Advanced Conditions
  • Experienced
  • Achalasia Microcephaly Syndrome
    Dr. Mathews is
    Experienced
    . Learn about Achalasia Microcephaly Syndrome.
    See more Achalasia Microcephaly Syndrome experts
  • Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease)
    Dr. Mathews is
    Experienced
    . Learn about Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease).
    See more Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease) experts
  • Andermann Syndrome
    Dr. Mathews is
    Experienced
    . Learn about Andermann Syndrome.
    See more Andermann Syndrome experts
  • Ataxia-Telangiectasia
    Dr. Mathews is
    Experienced
    . Learn about Ataxia-Telangiectasia.
    See more Ataxia-Telangiectasia experts
  • Brain Abscess
    Dr. Mathews is
    Experienced
    . Learn about Brain Abscess.
    See more Brain Abscess experts
  • Brain Herniation
    Dr. Mathews is
    Experienced
    . Learn about Brain Herniation.
    See more Brain Herniation experts
View All 35 Experienced Conditions
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