Amy Dezern
Distinguished in Anemia

Dr. Amy Dezern

Oncology | Hematology
Johns Hopkins Medicine
Sidney Kimmel Comprehensive Cancer Center
401 North Broadway Street, Weinberg BLDG, Weinberg BLDG, 
Baltimore, MD 
Clinical Trials:Currently Recruiting for 1 Trial
Offers Telehealth

Distinguished in Anemia
Johns Hopkins Medicine
Sidney Kimmel Comprehensive Cancer Center
401 North Broadway Street, Weinberg BLDG, Weinberg BLDG, 
Baltimore, MD 
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Overview

Dr. DeZern is a Professor of Oncology and Medicine at The Johns Hopkins University School of Medicine. She is active in the Division of Hematology Malignancies, Leukemia Program at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Dr. DeZern has expertise in aplastic anemia, myelodysplastic syndromes, paroxysmal nocturnal hemoglobinuria, acute myeloid leukemia, and bone marrow transplantation. Dr. DeZern received her medical degree at The Johns Hopkins University School of Medicine. She completed a residency in internal medicine at Johns Hopkins, followed by fellowships in medical oncology and hematology, as well as obtained a Masters in Clinical Investigations at the Bloomberg School of Public health. Dr. DeZern is a member of the American Society of Hematology, the American Society of Clinical Oncology, and the American Society for Transplantation and Cellular Therapy. Dr. DeZern’s principle research activities consist of designing and conducting clinical trials that test investigational new therapies and approaches in the treatment of bone marrow failure (aplastic anemia and myelodysplastic syndromes). She has specific expertise in the use of alternative donor bone marrow transplantation in patients with severe aplastic anemia and trials of novel therapeutics for patients with myelodysplastic syndromes. Additionally, she has taken a rigorous approach to the study of diagnostics and supportive case (such as transfusion practices) in these patient populations. She is or has been the Principal Investigator for a number of multicenter trials in collaboration with the MDS Clinical Research Consortium, the Eastern Co-operative Oncology Group (ECOG)-ACRIN and now the Bone Marrow Trials Clinical Trials Network (BMTCTN). She is the Study Chair for the multi-site BMTCTN study (CHAMP) investigating the role of haploidentical donor transplantation using post-transplantation cyclophosphamide in patients with relapsed several aplastic anemia. Dr. DeZern is the local PI as well as the Deputy Chair for The National MDS Study, a collaborative natural history study of the NHLBI and the NCI. As a clinical investigator with a focus on translation of novel treatments to the clinic, Dr. DeZern’s goal is to improve outcomes for patients with bone marrow failure at the bedside and in her research environment.

Dr. Dezern is rated as a Distinguished provider by MediFind in the treatment of Anemia. Her top areas of expertise are Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), Acute Myeloid Leukemia (AML), Bone Marrow Transplant, and Bone Marrow Aspiration.

Her clinical research consists of co-authoring 226 peer reviewed articles and participating in 10 clinical trials. MediFind looks at clinical research from the past 15 years. In particular, she has co-authored 45 articles and participated in 2 clinical trials in the study of Anemia.

Graduate Institution
Johns Hopkins Bloomberg School Of Public Health, MHS, 2011
Residency
Johns Hopkins University School of Medicine, Internal Medicine, 2008
Specialties
Oncology
Hematology
Licenses
Internal Medicine in MD
Board Certifications
American Board Of Internal Medicine
Fellowships
Johns Hopkins University School of Medicine, Oncology, 2012
Johns Hopkins University School of Medicine, Hematology and Oncology, 2009
Hospital Affiliations
Sibley Memorial Hospital
The Johns Hopkins Hospital
Languages Spoken
English
Gender
Female

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Locations

Sidney Kimmel Comprehensive Cancer Center
401 North Broadway Street, Weinberg BLDG, Weinberg BLDG, Baltimore, MD 21287
Call: 410-955-8964

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


10 Clinical Trials

Targeted Therapy With the IDH2-Inhibitor Enasidenib (AG221) for High-Risk IDH2-Mutant Myelodysplastic Syndrome
Targeted Therapy With the IDH2-Inhibitor Enasidenib (AG221) for High-Risk IDH2-Mutant Myelodysplastic Syndrome
Enrollment Status: Recruiting
Publish Date: August 13, 2025
Intervention Type: Other, Drug
Study Drugs: Azacitidine, Enasidenib
Study Phase: Phase 2
A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion
A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion
Enrollment Status: Active_not_recruiting
Publish Date: October 09, 2025
Intervention Type: Drug
Study Drug: Ruxolitinib
Study Phase: Phase 2
A Multicenter, Phase Ib/II Study That Combines Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients
A Multicenter, Phase Ib/II Study That Combines Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients
Enrollment Status: Suspended
Publish Date: August 05, 2025
Intervention Type: Drug
Study Drugs: Lenalidomide, Luspatercept
Study Phase: Phase 1/Phase 2
The National Myelodysplastic Syndromes Natural History Study
The National Myelodysplastic Syndromes Natural History Study
Enrollment Status: Active_not_recruiting
Publish Date: July 02, 2025
Intervention Type: Other
A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Tamibarotene Plus Azacitidine Versus Placebo Plus Azacitidine in Newly Diagnosed, Adult Patients Selected for RARA-positive Higher-risk Myelodysplastic Syndrome (SELECT MDS-1)
A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Tamibarotene Plus Azacitidine Versus Placebo Plus Azacitidine in Newly Diagnosed, Adult Patients Selected for RARA-positive Higher-risk Myelodysplastic Syndrome (SELECT MDS-1)
Enrollment Status: Terminated
Publish Date: April 10, 2025
Intervention Type: Drug
Study Drugs: SY-1425+Azacitidine, Azacitidine
Study Phase: Phase 3
A Phase 3, Randomized, Open-Label, Crossover Study of ASTX727 (Cedazuridine and Decitabine Fixed-Dose Combination) Versus IV Decitabine in Subjects With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), and Acute Myeloid Leukemia (AML)
A Phase 3, Randomized, Open-Label, Crossover Study of ASTX727 (Cedazuridine and Decitabine Fixed-Dose Combination) Versus IV Decitabine in Subjects With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), and Acute Myeloid Leukemia (AML)
Enrollment Status: Completed
Publish Date: August 27, 2024
Intervention Type: Drug
Study Drugs: Cedazuridine, Decitabine
Study Phase: Phase 3
A Phase1-2 Pharmacokinetic Guided Dose-Escalation and Dose-Confirmation Study of ASTX727, a Combination of the Oral Cytidine Deaminase Inhibitor (CDAi) E7727 With Oral Decitabine in Subjects With Myelodysplastic Syndromes (MDS)
A Phase1-2 Pharmacokinetic Guided Dose-Escalation and Dose-Confirmation Study of ASTX727, a Combination of the Oral Cytidine Deaminase Inhibitor (CDAi) E7727 With Oral Decitabine in Subjects With Myelodysplastic Syndromes (MDS)
Enrollment Status: Completed
Publish Date: August 27, 2024
Intervention Type: Drug
Study Phase: Phase 1/Phase 2
A Phase 1b/2, Open-label Clinical Study to Determine Preliminary Safety and Efficacy of Alvocidib When Administered in Sequence After Decitabine or Azacitidine in Patients With MDS
A Phase 1b/2, Open-label Clinical Study to Determine Preliminary Safety and Efficacy of Alvocidib When Administered in Sequence After Decitabine or Azacitidine in Patients With MDS
Enrollment Status: Terminated
Publish Date: November 09, 2023
Intervention Type: Combination product
Study Drugs: Alvocidib, Decitabine, Azacitidine
Study Phase: Phase 1/Phase 2
A Phase II Trial of Non-Myeloablative Conditioning and Transplantation of Partially HLA-Mismatched/Haploidentical Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes
A Phase II Trial of Non-Myeloablative Conditioning and Transplantation of Partially HLA-Mismatched/Haploidentical Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes
Enrollment Status: Completed
Publish Date: March 10, 2023
Intervention Type: Drug, Radiation, Procedure
Study Drugs: Thymoglobulin, Fludarabine, Cyclophosphamide, Mesna, Tacrolimus, Mycophenolic Acid Mofetil
Study Phase: Phase 2
A Phase 1b/2 Study to Evaluate the Safety and Efficacy of APR-246 in Combination With Azacitidine for the Treatment of TP53 Mutant Myeloid Neoplasms
A Phase 1b/2 Study to Evaluate the Safety and Efficacy of APR-246 in Combination With Azacitidine for the Treatment of TP53 Mutant Myeloid Neoplasms
Enrollment Status: Completed
Publish Date: January 24, 2022
Intervention Type: Drug
Study Drugs: APR-246, Azacitidine
Study Phase: Phase 1/Phase 2
View 9 Less Clinical Trials

226 Total Publications

A PBD-dimer containing antibody drug conjugate targeting CCRL2 for high-risk MDS/AML.
A PBD-dimer containing antibody drug conjugate targeting CCRL2 for high-risk MDS/AML.
Journal: Research square
Published: November 24, 2025
View All 226 Publications
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 (15.6 miles away)
410-955-8964
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Dr. Robert Brodsky is a professor of medicine at the Johns Hopkins University School of Medicine. His area of clinical expertise is classical hematology and haploidentical bone marrow transplant for sickle cell disease and aplastic anemia. Dr. Brodsky serves as the director of the Division of Hematology and the T32 Training Program. He is the Johns Hopkins Family Professor of Medicine and Oncology. He received his M.D. from Hahnemann University. He completed his residency at the Vanderbilt University School of Medicine. He performed a fellowship in hematology at the National Institutes of Health and a fellowship in oncology at Johns Hopkins. He joined the Johns Hopkins faculty in 1997. From 2017 to 2022 he served as Associate Editor to The Journal of Clinical Investigation (JCI) and Secretary to American Society of Hematology (ASH). He serves as President of The American Society of Hematology (ASH) in 2023. Dr. Brodsky is rated as an Elite provider by MediFind in the treatment of Anemia. His top areas of expertise are Paroxysmal Nocturnal Hemoglobinuria (PNH), Paroxysmal Cold Hemoglobinuria, Anemia, Bone Marrow Transplant, and Splenectomy.

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Dr. Lydia H. Pecker is a pediatric hematologist and Director of the Young Adult Clinic at the Sickle Cell Center for Adults at Johns Hopkins. Dr. Pecker received her undergraduate degree in Africana studies from Brown University and earned her M.D. at the University of Pennsylvania School of Medicine. She completed residency training at Children’s Hospital at Montefiore and completed a fellowship at Children’s National Medical Center and the National Institutes of Health’s National Heart, Lung and Blood Institute before joining the Hopkins faculty in 2016. Dr. Pecker's NIH and foundation-funded research focuses on reproductive health in people with ovaries and sickle cell disease. Dr. Pecker is rated as a Distinguished provider by MediFind in the treatment of Anemia. Her top areas of expertise are Sickle Cell Disease, Congenital Hemolytic Anemia, Hemoglobinopathy, Hemolytic Anemia, and Tubal Ligation.

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Areas of Expertise

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Find Dr. Dezern's expertise for a condition
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  • Elite
  • Acute Myeloid Leukemia (AML)
    Dr. Dezern is
    Elite
    . Learn about Acute Myeloid Leukemia (AML).
    See more Acute Myeloid Leukemia (AML) experts
  • Aplastic Anemia
    Dr. Dezern is
    Elite
    . Learn about Aplastic Anemia.
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  • Chronic Myelomonocytic Leukemia (CMML)
    Dr. Dezern is
    Elite
    . Learn about Chronic Myelomonocytic Leukemia (CMML).
    See more Chronic Myelomonocytic Leukemia (CMML) experts
  • Myelodysplastic Syndrome (MDS)
    Dr. Dezern is
    Elite
    . Learn about Myelodysplastic Syndrome (MDS).
    See more Myelodysplastic Syndrome (MDS) experts
  • Sideroblastic Anemia
    Dr. Dezern is
    Elite
    . Learn about Sideroblastic Anemia.
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  • Distinguished
  • Acute Myeloblastic Leukemia with Maturation
    Dr. Dezern is
    Distinguished
    . Learn about Acute Myeloblastic Leukemia with Maturation.
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  • Acute Myeloblastic Leukemia without Maturation
    Dr. Dezern is
    Distinguished
    . Learn about Acute Myeloblastic Leukemia without Maturation.
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  • Anemia
    Dr. Dezern is
    Distinguished
    . Learn about Anemia.
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  • Ataxia-Pancytopenia Syndrome
    Dr. Dezern is
    Distinguished
    . Learn about Ataxia-Pancytopenia Syndrome.
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  • Bone Marrow Transplant
    Dr. Dezern is
    Distinguished
    . Learn about Bone Marrow Transplant.
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  • Childhood Acute Myeloid Leukemia
    Dr. Dezern is
    Distinguished
    . Learn about Childhood Acute Myeloid Leukemia.
    See more Childhood Acute Myeloid Leukemia experts
View All 13 Distinguished Conditions
  • Advanced
  • Acute Erythroid Leukemia (AEL)
    Dr. Dezern is
    Advanced
    . Learn about Acute Erythroid Leukemia (AEL).
    See more Acute Erythroid Leukemia (AEL) experts
  • Acute Lymphoblastic Leukemia (ALL)
    Dr. Dezern is
    Advanced
    . Learn about Acute Lymphoblastic Leukemia (ALL).
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  • Acute Promyelocytic Leukemia
    Dr. Dezern is
    Advanced
    . Learn about Acute Promyelocytic Leukemia.
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  • Agranulocytosis
    Dr. Dezern is
    Advanced
    . Learn about Agranulocytosis.
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  • Bone Marrow Aspiration
    Dr. Dezern is
    Advanced
    . Learn about Bone Marrow Aspiration.
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  • Febrile Neutropenia
    Dr. Dezern is
    Advanced
    . Learn about Febrile Neutropenia.
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View All 9 Advanced Conditions
  • Experienced
  • Aleukemic Leukemia Cutis (ALC)
    Dr. Dezern is
    Experienced
    . Learn about Aleukemic Leukemia Cutis (ALC).
    See more Aleukemic Leukemia Cutis (ALC) experts
  • Chronic Familial Neutropenia
    Dr. Dezern is
    Experienced
    . Learn about Chronic Familial Neutropenia.
    See more Chronic Familial Neutropenia experts
  • Chronic Myelogenous Leukemia (CML)
    Dr. Dezern is
    Experienced
    . Learn about Chronic Myelogenous Leukemia (CML).
    See more Chronic Myelogenous Leukemia (CML) experts
  • Diffuse Large B-Cell Lymphoma (DLBCL)
    Dr. Dezern is
    Experienced
    . Learn about Diffuse Large B-Cell Lymphoma (DLBCL).
    See more Diffuse Large B-Cell Lymphoma (DLBCL) experts
  • Hemoglobinopathy
    Dr. Dezern is
    Experienced
    . Learn about Hemoglobinopathy.
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  • Hemolytic Anemia
    Dr. Dezern is
    Experienced
    . Learn about Hemolytic Anemia.
    See more Hemolytic Anemia experts
View All 17 Experienced Conditions
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