James S. Gammie
Advanced in Endocarditis

Dr. James S. Gammie

Thoracic Surgery
Johns Hopkins Medicine
Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
10755 Falls Road, Pavilion I STE 360, Pavilion I STE 360, 
Lutherville, MD 
Clinical Trials:Currently Recruiting for 2 Trials
Offers Telehealth

Advanced in Endocarditis
Johns Hopkins Medicine
Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
10755 Falls Road, Pavilion I STE 360, Pavilion I STE 360, 
Lutherville, MD 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

James Gammie is the surgical lead and co-director for the Johns Hopkins Heart and Vascular Institute and cardiac surgeon-in-chief for the Johns Hopkins Health System. With over 23 years of experience in cardiothoracic surgery, Dr. Gammie joined Johns Hopkins after serving as chief of the division of cardiac surgery at the University of Maryland Medical Center from 2012 to 2021. Dr. Gammie graduated from Brown University with a degree in biochemistry, and received his medical degree from the University of Massachusetts Medical School. Dr. Gammie trained in both general and cardiothoracic surgery at the University of Pittsburgh School of Medicine. His clinical and research efforts are focused on decreasing the mortality and morbidity of valve disease and improving the surgical treatment of mitral valve and other structural heart diseases. He performs over 225 mitral valve operations and interventions per year, and leads a cardiac surgery team that performs more than 1,200 cardiac operations annually. He is recognized by the Mitral Foundation and the American Heart Association as one of less than 25 reference surgeons in the U.S. for his experience in mitral valve repair and excellent patient outcomes. Dr. Gammie has a strong interest in all aspects of heart valve disease, and has published more than 200 peer-reviewed contributions in leading specialty journals including The New England Journal of Medicine, the Journal of Thoracic and Cardiovascular Surgery and Circulation. He has served as a deputy editor for The Annals of Thoracic Surgery and as chair of the Access and Publications Committee of the Society of Thoracic Surgeons Adult Cardiac Surgery Database. He serves on the steering committee of the NHLBI-sponsored Cardiothoracic Surgery Trials Network, and led the protocol development committee of a worldwide randomized tricuspid valve surgery trial. He is a member of the Halsted Society and the 21st Century Cardiothoracic Surgical Society. In 2011, Dr. Gammie was awarded the Johns Hopkins/University of Maryland Alliance for Science and Technology Development BioMaryland LIFE Prize, and he was named Entrepreneur of the Year at the University of Maryland Baltimore in 2014. He is the inventor of a novel transseptal catheter designed to simplify transcatheter cardiac procedures, and founded a commercial company to commercialize the device. With 20 issued or submitted patents, he continues to innovate in the mitral valve space, and recently published the world’s first clinical experience with a novel surgical repair for secondary mitral valve regurgitation, which was developed in his laboratory: mitral valve translocation. From 2016–2021, Dr. Gammie was consistently named a Top Doctor by Baltimore magazine, and in 2018 he received the Golden Apple Teacher of the Year award.

Dr. Gammie is rated as an Advanced provider by MediFind in the treatment of Endocarditis. His top areas of expertise are Mitral Valve Regurgitation, Tricuspid Regurgitation, Mitral Valve Prolapse, Embolectomy, and Heart Bypass Surgery.

His clinical research consists of co-authoring 195 peer reviewed articles and participating in 10 clinical trials. MediFind looks at clinical research from the past 15 years. In particular, he has co-authored 11 articles in the study of Endocarditis.

Residency
UPMC-University of Pittsburgh Medical Center, General Surgery, 1995
Specialties
Thoracic Surgery
Licenses
Specialist in MD
Board Certifications
American Board Of Thoracic Surgery
Fellowships
UPMC-University of Pittsburgh Medical Center, Thoracic Surgery, 1999
Hospital Affiliations
The Johns Hopkins Hospital
Languages Spoken
English
Gender
Male

Insurance

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
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Cigna
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Locations

Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
10755 Falls Road, Pavilion I STE 360, Pavilion I STE 360, Lutherville, MD 21093
Call: 410-955-2800

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


10 Clinical Trials

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Enrollment Status: Recruiting
Publish Date: February 07, 2025
Intervention Type: Drug
Study Drugs: Antiplatelet-only strategy, Anticoagulant+Background antiplatelet therapy
Study Phase: Phase 3
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Enrollment Status: Recruiting
Publish Date: January 31, 2025
Intervention Type: Device
Study Phase: Not Applicable
Medtronic PERIcardial SurGical AOrtic Valve ReplacemeNt Pivotal Trial A Multi-center, Non-randomized Trial to Determine the Safety and Effectiveness of the Model 400 Aortic Valve Bioprosthesis in Patients With Aortic Valve Disease
Medtronic PERIcardial SurGical AOrtic Valve ReplacemeNt Pivotal Trial A Multi-center, Non-randomized Trial to Determine the Safety and Effectiveness of the Model 400 Aortic Valve Bioprosthesis in Patients With Aortic Valve Disease
Enrollment Status: Active_not_recruiting
Publish Date: October 16, 2025
Intervention Type: Device
Study Phase: Not Applicable
Edwards EVOQUE Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy Using a Novel Device
Edwards EVOQUE Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy Using a Novel Device
Enrollment Status: Active_not_recruiting
Publish Date: October 09, 2025
Intervention Type: Device, Drug
Study Phase: Not Applicable
Edwards EVOQUE Tricuspid Valve Replacement: Investigation of Safety and Clinical Efficacy After Replacement of Tricuspid Valve With Transcatheter Device
Edwards EVOQUE Tricuspid Valve Replacement: Investigation of Safety and Clinical Efficacy After Replacement of Tricuspid Valve With Transcatheter Device
Enrollment Status: Active_not_recruiting
Publish Date: August 15, 2025
Intervention Type: Device
Study Phase: Not Applicable
Long-Term Follow-Up For Participants Of: Evaluation Of Outcomes Following Mitral Valve Repair/Replacement In SMR and Surgical Interventions For MMR Trials
Long-Term Follow-Up For Participants Of: Evaluation Of Outcomes Following Mitral Valve Repair/Replacement In SMR and Surgical Interventions For MMR Trials
Enrollment Status: Active_not_recruiting
Publish Date: July 16, 2025
Intervention Type: Other
AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment During Concomitant On-Pump Endo/Epicardial Cardiac Surgery
AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment During Concomitant On-Pump Endo/Epicardial Cardiac Surgery
Enrollment Status: Active_not_recruiting
Publish Date: October 15, 2024
Intervention Type: Device
Study Phase: Not Applicable
Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery
Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery
Enrollment Status: Completed
Publish Date: June 18, 2024
Intervention Type: Procedure
Study Phase: Not Applicable
A Clinical Evaluation of the Safety and Effectiveness of the MitraClip® System for the Treatment of Functional Mitral Regurgitation in Symptomatic Heart Failure Subjects (COAPT Recruitment Closed). COAPT CAS (Recruitment Closed)
A Clinical Evaluation of the Safety and Effectiveness of the MitraClip® System for the Treatment of Functional Mitral Regurgitation in Symptomatic Heart Failure Subjects (COAPT Recruitment Closed). COAPT CAS (Recruitment Closed)
Enrollment Status: Unknown
Publish Date: November 27, 2023
Intervention Type: Device
Study Phase: Not Applicable
A Prospective Randomized Trial of Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Mitral Operation
A Prospective Randomized Trial of Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Mitral Operation
Enrollment Status: Completed
Publish Date: May 08, 2023
Intervention Type: Procedure, Other
Study Phase: Not Applicable
View 8 Less Clinical Trials

195 Total Publications

The ICE-AFIB trial: A multicenter prospective investigational device exemption (IDE) trial using cryosurgical ablation for atrial fibrillation during concomitant cardiac surgery.
The ICE-AFIB trial: A multicenter prospective investigational device exemption (IDE) trial using cryosurgical ablation for atrial fibrillation during concomitant cardiac surgery.
Journal: The Journal of thoracic and cardiovascular surgery
Published: September 02, 2025
View All 195 Publications
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Thomas Macgillivray is a Thoracic Surgeon in Washington, Washington, D.c.. Dr. Macgillivray is rated as a Distinguished provider by MediFind in the treatment of Endocarditis. His top areas of expertise are Heart Tumor, Aortic Valve Stenosis, Pulmonary Fibrosis, Heart Transplant, and Aortic Valve Replacement.

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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

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  • Elite
  • Mitral Valve Regurgitation
    Dr. Gammie is
    Elite
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  • Distinguished
  • Embolectomy
    Dr. Gammie is
    Distinguished
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  • Heart Bypass Surgery
    Dr. Gammie is
    Distinguished
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  • Tricuspid Regurgitation
    Dr. Gammie is
    Distinguished
    . Learn about Tricuspid Regurgitation.
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  • Advanced
  • Coronary Artery Bypass Graft (CABG)
    Dr. Gammie is
    Advanced
    . Learn about Coronary Artery Bypass Graft (CABG).
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  • Endocarditis
    Dr. Gammie is
    Advanced
    . Learn about Endocarditis.
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  • Heart Valve Repair
    Dr. Gammie is
    Advanced
    . Learn about Heart Valve Repair.
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  • Infective Endocarditis
    Dr. Gammie is
    Advanced
    . Learn about Infective Endocarditis.
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  • Mitral Stenosis
    Dr. Gammie is
    Advanced
    . Learn about Mitral Stenosis.
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  • Mitral Valve Prolapse
    Dr. Gammie is
    Advanced
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View All 8 Advanced Conditions
  • Experienced
  • Acute Respiratory Distress Syndrome (ARDS)
    Dr. Gammie is
    Experienced
    . Learn about Acute Respiratory Distress Syndrome (ARDS).
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  • Aortic Dissection
    Dr. Gammie is
    Experienced
    . Learn about Aortic Dissection.
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  • Aortic Regurgitation
    Dr. Gammie is
    Experienced
    . Learn about Aortic Regurgitation.
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  • Aortic Valve Replacement
    Dr. Gammie is
    Experienced
    . Learn about Aortic Valve Replacement.
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  • Aortic Valve Stenosis
    Dr. Gammie is
    Experienced
    . Learn about Aortic Valve Stenosis.
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  • Arterial Embolism
    Dr. Gammie is
    Experienced
    . Learn about Arterial Embolism.
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View All 25 Experienced Conditions
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