Dr. Aristea S. Galanopoulou

The maturation of GABAA receptor-mediated signaling from depolarizing to inhibitory is an age-related process controlled by cation chloride cotransporters, such as KCC2. As a result, GABA exerts dual functions, being an important neurotrophic factor during early development and the principal inhibitory neurotransmitter of the mature central nervous system. In our laboratory we have been investigating the age and mechanisms through which early life stressors and seizures may disrupt the normal patterns of brain development, by disrupting the neurotrophic effects of GABA. We are also studying methods to reverse these adverse processes. Furthermore, we are very interested in understanding how epileptogenesis proceeds in the developing brain and what is the specific role of GABAA receptors in this process.

Dr. Galanopoulou is highly rated in 9 conditions, according to our data. Her clinical expertise encompasses West Syndrome, Spasmus Nutans, Post-Traumatic Epilepsy, and Epilepsy.

She is actively involved in clinical research, co-authoring 130 peer reviewed articles.