William E. Karnes
Expertise in
13
conditions
Expertise in
13
conditions
101 The City Drive South, Building 22C, 
Orange, CA 

Overview

Dr. William E. Karnes is a board-certified UCI Health gastroenterologist who specializes in disorders of the gastrointestinal tract, including colorectal cancer screening, gastrointestinal reflux disease (GERD), swallowing disorders, irritable bowel syndrome, peptic ulcers and esophageal disorders.He performs colonoscopies, upper endoscopies and capsule endoscopies, and treats gastrointestinal bleeding, chronic diarrhea, constipation, bloating and bacterial problems in the small intestines.Karnes earned his medical degree from the University of Minnesota Medical School in Minneapolis, where he completed a residency in internal medicine. He went on to complete a fellowship in molecular biology at Mayo Clinic in Rochester, Minn., and a fellowship in gastroenterology at the University of California, Los Angeles.His research interests include colon cancer screening, risk assessment for colon cancer and artificial intelligence-assisted colonoscopy. He also conducts translational research on colon cancer prevention, with an emphasis on regular colorectal screening, especially among patients and families with a genetic risk for developing the disease.

Dr. Karnes is highly rated in 13 conditions, according to our data. His clinical expertise encompasses Trichohepatoenteric Syndrome, Nonalcoholic Steatohepatitis (NASH), Familial Adenomatous Polyposis, Endoscopy, and Gastrectomy.

Dr. Karnes is board certified in American Board Of Internal Medicine - Gastroenterology and American Board Of Internal Medicine - Internal Medicine.

Graduate Institution

University Of Minnesota

Residency

University of Minnesota - Internal Medicine

Specialties

Gastroenterology
Internal Medicine

Licenses

Internal Medicine in CA

Board Certifications

American Board Of Internal Medicine - Gastroenterology
American Board Of Internal Medicine - Internal Medicine

Fellowships

UCLA Medical Center - Gastroentrology and Hepatology Fellowship
Mayo School of Graduate Education - Research Fellowship in Gastroenterology

Hospital Affiliations

Uci Health-Orange
Hoag Memorial Hospital Presbyterian

Languages Spoken

English

Gender

Male

Awards

Physicians of Excellence
Orange County Medical Association – 2021
Best Doctors in America® — Gastroenterology
2015
2016
American Federation of Clinical Research Award
1995
Young Scholar Award
World Congress of Gastroenterology
1994
National Institutes of Health Fellowship Training grants
1987-88 and 1990-92
Merck Fellowship Training Grant
1987-88

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
Alignment Health Plan
  • MEDICARE MAPD
  • MEDICARE SNP
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
Anthem BCBS
  • EPO
  • HMO
  • POS
  • PPO
Blue Cross Blue Shield
  • EPO
  • HMO
  • POS
  • PPO
Blue Shield of California
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE-MEDICAID PLAN
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
  • PPO
Cambia Health Solutions
  • EPO
  • INSURANCE PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • PPO
CareFirst
  • HMO
  • POS
  • PPO
Change Healthcare
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
Cigna
  • EPO
  • HMO
  • PPO
Health Care Services Corporation
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
  • PPO
Health Net

Accepted plan types not found. Please verify directly with the provider.

Horizon Healthcare
  • EPO
  • POS
Humana
  • HMO
  • INDEMNITY
  • POS
  • PPO
Kaiser Permanente
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • OTHER MEDICARE
  • POS
  • PPO
Managed Medicaid
  • OTHER MANAGED MEDICAID
Medicaid
  • OTHER MEDICAID
  • STATE MEDICAID
Medicare
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE PART D
Nippon Life
  • INSURANCE PLAN
Northern Plains Alliance
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE PDP
Oscar
  • EPO
  • HMO
  • PPO
Premera Blue Cross
  • INSURANCE PLAN
  • MEDICARE MAPD
  • OTHER COMMERCIAL
  • PPO
SCAN Health Plan
  • INSURANCE PLAN
  • MEDICARE MAPD
UnitedHealthcare
  • EPO
  • HMO
  • POS
  • PPO
Walgreens
  • MEDICARE DISCOUNT CARD
  • MEDICARE PDP
  • OTHER MEDICARE
Wellcare
  • EPO
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
View 20 Less Insurance Carriers -

Locations

UCI Health Chao Family Comprehensive Digestive Disease Center
101 The City Drive South, Building 22C, Orange, CA 92868
Other Locations
Gottschalk Medical Plaza
1 Medical Plaza Drive, Irvine, CA 92697
UCI Health - Costa Mesa
1640 Newport Boulevard, Suite 100, Mesa, CA 92627

Additional Areas of Focus

Dr. Karnes has provided the following conditions as areas of focus. Please note that we may not have enough data to validate their experience in some of these conditions.

Gastrointestinal Bleeding
Gastroesophageal Reflux Disease (GERD)
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Languages Spoken:
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Frequently Asked Questions about Dr. William E. Karnes

How do I make an appointment with Dr. William E. Karnes?

You can book an appointment with Dr. William E. Karnes by calling their office at 888-717-4463. MediFind provides direct contact information so you can schedule visits, second opinions, or consultations without navigating third-party calendars.

Is Dr. William E. Karnes a top-rated expert for Trichohepatoenteric Syndrome?

MediFind is an objective health platform that identifies experts based on real-world data. Dr. William E. Karnes is classified as an Distinguished expert for Trichohepatoenteric Syndrome, meaning they are among the top experts in the country for this condition. This ranking is based on their volume of patients, published research, and peer connections.

What conditions does Dr. William E. Karnes specialize in?

While Dr. William E. Karnes is a Gastroenterology, they have specific expertise in Trichohepatoenteric Syndrome, Nonalcoholic Steatohepatitis (NASH), and Familial Adenomatous Polyposis. MediFind analyzes a doctor's articles and referral patterns to identify their specific areas of focus within Gastroenterology.

Does Dr. William E. Karnes accept my insurance?

Dr. William E. Karnes accepts most major insurance plans, including Aetna and Alignment Health Plan. We recommend calling the office directly at 888-717-4463 to verify that your specific plan is currently accepted before your visit.

Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

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