Expertise in
32
conditions

Dr. Daniel M. Trifiletti

Radiation Oncology
FL - Cancer
4500 San Pablo Rd S, 
Jacksonville, FL 
Clinical Trials:Currently Recruiting for 3 Trials
Accepting New Patients
Offers Telehealth
Expertise in
32
conditions
FL - Cancer
4500 San Pablo Rd S, 
Jacksonville, FL 

Overview

Daniel Trifiletti is a Radiation Oncologist practicing medicine in Jacksonville, Florida.

Dr. Trifiletti is highly rated in 32 conditions, according to our data. His clinical expertise encompasses Astrocytoma, Brain Tumor, Glioblastoma, Gamma Knife Radiosurgery, and Thalamotomy.

He is actively involved in clinical research, co-authoring 270 peer reviewed articles and participating in 5 clinical trials. Dr. Trifiletti is currently accepting new patients.

Graduate Institution

University Of Florida College Of Medicine

Specialties

Radiation Oncology

Licenses

Radiology in FL

Hospital Affiliations

Mayo Clinic

Languages Spoken

English

Gender

Male

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
Anthem BCBS
  • EPO
  • HMO
  • POS
  • PPO
Blue Cross Blue Shield
  • EPO
  • HMO
  • POS
  • PPO
CareFirst
  • HMO
  • POS
  • PPO
Cigna
  • EPO
  • HMO
  • PPO
Florida Blue
  • EPO
  • PPO
Health Options
  • HMO
  • POS
  • PPO
Humana
  • HMO
  • INDEMNITY
  • POS
  • PPO
Simply Healthcare
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • OTHER MEDICARE PART D
UnitedHealthcare
  • EPO
  • HMO
  • POS
  • PPO
Wellcare
  • EPO
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
View 6 Less Insurance Carriers -

Locations

FL - Cancer
4500 San Pablo Rd S, Jacksonville, FL 32224

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.

5 Clinical Trials

Pre-Operative vs. Post-Operative Stereotactic Radiosurgery for Operative Metastatic Brain Tumors
Pre-Operative vs. Post-Operative Stereotactic Radiosurgery for Operative Metastatic Brain Tumors
Enrollment Status: Recruiting
Publish Date: August 19, 2026
Intervention Type: Procedure, Radiation, Other
Study Phase: Phase 3
Preoperative Radiosurgery in High Grade Glioma: A Phase I Clinical Trial: The NeoGlioma Study
Preoperative Radiosurgery in High Grade Glioma: A Phase I Clinical Trial: The NeoGlioma Study
Enrollment Status: Recruiting
Publish Date: August 17, 2026
Intervention Type: Procedure, Drug, Radiation
Study Drug: Temozolomide
Study Phase: Phase 1
A Phase III Trial of Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
A Phase III Trial of Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
Enrollment Status: Recruiting
Publish Date: June 09, 2026
Intervention Type: Radiation, Procedure, Drug
Study Drug: Memantine
Study Phase: Phase 3
Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).
Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).
Enrollment Status: Completed
Publish Date: October 31, 2025
Intervention Type: Device, Other
Study Phase: Phase 3
18F-Fluciclovine PET Discrimination of Radiation Injury to the Brain
18F-Fluciclovine PET Discrimination of Radiation Injury to the Brain
Enrollment Status: Terminated
Publish Date: September 10, 2025
Intervention Type: Other, Radiation
View 2 Less Clinical Trial

270 Total Publications

Role of radiosurgical thalamotomy in the management for essential tremor: evidence from an international multi-institutional study.
Role of radiosurgical thalamotomy in the management for essential tremor: evidence from an international multi-institutional study.
Journal: Journal of neurology
Published: May 19, 2026
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Frequently Asked Questions about Dr. Daniel M. Trifiletti

How do I make an appointment with Dr. Daniel M. Trifiletti?

You can book an appointment with Dr. Daniel M. Trifiletti by calling their office at 904-914-7532. MediFind provides direct contact information so you can schedule visits, second opinions, or consultations without navigating third-party calendars.

Is Dr. Daniel M. Trifiletti a top-rated expert for Astrocytoma?

MediFind is an objective health platform that identifies experts based on real-world data. Dr. Daniel M. Trifiletti is classified as an Elite expert for Astrocytoma, meaning they are among the top experts in the country for this condition. This ranking is based on their volume of patients, published research, and peer connections.

What conditions does Dr. Daniel M. Trifiletti specialize in?

While Dr. Daniel M. Trifiletti is a Radiation Oncology, they have specific expertise in Astrocytoma, Brain Tumor, and Glioblastoma. MediFind analyzes a doctor's articles and referral patterns to identify their specific areas of focus within Radiation Oncology.

Does Dr. Daniel M. Trifiletti participate in research or clinical trials?

Yes. Dr. Daniel M. Trifiletti has published 270 articles and abstracts on conditions like Astrocytoma. You can view a list of Dr. Daniel M. Trifiletti's latest peer-reviewed publications and clinical trial participation on their profile to see if they are active in new treatments.

Does Dr. Daniel M. Trifiletti accept my insurance?

Dr. Daniel M. Trifiletti accepts most major insurance plans, including Aetna and Anthem BCBS. We recommend calling the office directly at 904-914-7532 to verify that your specific plan is currently accepted before your visit.

Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

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